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    Article

    Selenoneine Is Methylated in the Bodies of Mice and then Excreted in Urine as Se-Methylselenoneine

    Oral intake of purified selenoneine and seafoods has been reported to result in selenoneine accumulation in erythrocytes in mice and human. In addition, Se-methylselenoneine was suggested to be produced as a m...

    Takuya Seko, Hajime Uchida, Yoko Sato in Biological Trace Element Research (2024)

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    Article

    Pancreatic cancer detection with dual-energy CT: diagnostic performance of 40 keV and 70 keV virtual monoenergetic images

    To compare the diagnostic performance of 40 keV and 70 keV virtual monoenergetic images (VMIs) generated from dual-energy CT in the detection of pancreatic cancer.

    Yoshifumi Noda, Tomohiro Ando, Tetsuro Kaga, Nao Yamda, Takuya Seko in La radiologia medica (2024)

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    Article

    Consumer preference for label presentations of freshness, taste, and serving suggestion on fresh fish packages of Japanese flounder Paralichthys olivaceus

    Understanding consumer choice behavior for seafood is important for the efficient and sustainable use of marine resources and the improvement of human health. This study aims to identify the information conten...

    Ryutaro Kamiyama, Hiroki Wakamatsu, Takuya Seko, Kenji Ishihara in Fisheries Science (2024)

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    Article

    Distribution and Effects of Selenoneine by Ingestion of Extract from Mackerel Processing Residue in Mice

    Selenoneine is an organic selenium compound contained in blood and dark muscle of fish. It has a strong antioxidative capacity and is considered useful as a new functional food material. However, the distribut...

    Takuya Seko, Yoko Sato, Michiko Kuniyoshi, Yuko Murata in Marine Biotechnology (2023)

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    Article

    Selenoneine suppresses melanin synthesis by inhibiting tyrosinase in murine B16 melanoma cells and 3D-cultured human melanocytes

    The novel organic selenium compound, selenoneine, is found in the blood of tuna and has metal-binding activity. In this report, selenoneine displays tyrosinase inhibitory activity. When murine B16 melanoma cel...

    Takuya Seko, Shintaro Imamura, Kenji Ishihara, Yumiko Yamashita in Fisheries Science (2020)

  6. Article

    Open Access

    Mandibular prognathism attenuates brain blood flow induced by chewing

    Mastication is closely related to brain function. Animal experiments have revealed that tooth loss has a negative influence on brain function. Clinical studies also suggest that normal occlusion is an essentia...

    Hiroyuki Kanzaki, Satoshi Wada, Masao Kumazawa, Yuko Yamada in Scientific Reports (2019)

  7. Article

    Open Access

    Inhibition of angiotensin-converting enzyme by selenoneine

    Selenoneine is a selenium-containing compound that exhibits strong radical-scavenging activity. Here we present a novel function of selenium in which selenoneine exhibits inhibitory activity against angiotensi...

    Takuya Seko, Shintaro Imamura, Kenji Ishihara, Yumiko Yamashita in Fisheries Science (2019)

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    Chapter and Conference Paper

    Representation, Analysis and Processing of Student Counseling Cases

    Student counseling becomes an important roles in University.Many colleges have been paying effort for the task. The field of student counseling has not introduced computational technique. The paper challenges ...

    Naotaka Oda, Aya Nishimura, Takuya Seko in Software Engineering, Artificial Intellige… (2013)