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Article
Correction: Clinical features of patients with hepatocellular carcinoma treated with radiofrequency ablation therapy: develo** a simple score to determine the need for immune-adjuvant therapy
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Article
C-Reactive Protein-Albumin Ratio Predicts Objective Response to Enfortumab Vedotin in Metastatic Urothelial Carcinoma
Enfortumab vedotin (EV), an antibody-drug conjugate that targets Nectin-4, is used for patients with metastatic urothelial carcinoma who have experienced progression on platinum-based chemotherapy and checkpoi...
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Article
Clinical features of patients with hepatocellular carcinoma treated with radiofrequency ablation therapy: develo** a simple score to determine the need for immune-adjuvant therapy
Unresectable recurrence after curative treatments for hepatocellular carcinoma (HCC) is a life-limited event. Although the IMbrave050 trial (IM050) showed a favorable reduction in recurrence with adjuvant immu...
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Article
Durable Response to Enfortumab Vedotin Compared to Re-challenging Chemotherapy in Metastatic Urothelial Carcinoma After Checkpoint Inhibitors
Enfortumab vedotin (EV), an antibody–drug conjugate targeting Nectin-4, has been used for patients with metastatic urothelial carcinoma (mUC) after progressing on checkpoint inhibitors (CPIs). Re-challenging c...
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Chapter and Conference Paper
Neural Additive and Basis Models with Feature Selection and Interactions
Deep neural networks (DNNs) exhibit attractive performance in various fields but often suffer from low interpretability. The neural additive model (NAM) and its variant called the neural basis model (NBM) use ...
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Article
Bim downregulation by activation of NF-κB p65, Akt, and ERK1/2 is associated with adriamycin and dexamethasone resistance in multiple myeloma cells
Multiple myeloma (MM) frequently acquires multidrug resistance (MDR), which is due to poor prognosis. Our previous study indicated that high expression of Survivin and multidrug resistance protein 1 (MDR1) and...
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Article
Allograft adenovirus nephritis accompanied by Crohn’s disease in a kidney transplant recipient: a novel case report
Excessive immunosuppression after kidney transplantation (KT) is often encountered in patients undergoing therapy for anti-rejection or autoimmune disease that requires further treatment using immunosuppressiv...
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Article
Open AccessStatins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy
KRAS mutations are fraught with the progression of colorectal cancer and resistance to chemotherapy. There are pathways such as extracellular regulated protein kinase 1/2 (ERK1/2) and Akt downstream and farnes...
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Article
Prodigiosin R3, a new multicyclic prodigiosin formed by prodigiosin cyclization genes in the roseophilin producer
The rph gene cluster for prodigiosin biosynthesis has been identified in Streptomyces griseoviridis 2464-S5, which produces cyclic prodigiosin derivatives including roseophilin (2), prodigiosin R1 (3) and prodigi...
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Article
Inhibition of yes-associated protein suppresses migration, invasion, and metastasis in non-small cell lung cancer in vitro and in vivo
Non-small cell lung cancer (NSCLC) is a highly aggressive cancer with one of the most prevalent malignant tumors. Metastasis in NSCLC is the major cause of treatment failure and cancer-related deaths. Yes-asso...
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Article
Usefulness of albumin–globulin ratio as a clinical prognostic factor in patients with thyroid cancer treated with radioiodine
Albumin–globulin ratio (AGR), which is calculated by dividing serum albumin by serum globulin, is considered as a cancer-related inflammation biomarker. Although the prognosis of many solid cancers has been sh...
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Article
Open AccessUnilateral lower limb atrophy associated with glomus tumors: a case report
Glomus tumors are soft tissue neoplasms comprised of glomus cells, vasculature, and smooth muscle cells, which occur commonly in a single subungual area of the digits, and their main clinical features include ...
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Article
Open AccessA surgically treated case of severe upper gastrointestinal hemorrhage with gastritis cystica polyposa
Gastritis cystica polyposa (GCP) is a recently recognized entity histologically characterized by hyperplasia and cystic dilatation of the gastric glands spreading through the submucosal layer. Its symptoms inc...
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Article
Open AccessComputed tomographic evaluation of myocardial ischemia
Myocardial ischemia is caused by a mismatch between myocardial oxygen consumption and oxygen delivery in coronary artery disease (CAD). Stratification and decision-making based on ischemia improves the prognos...
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Article
Open AccessRoom-temperature terahertz anomalous Hall effect in Weyl antiferromagnet Mn3Sn thin films
Antiferromagnetic spin motion at terahertz (THz) frequencies attracts growing interests for fast spintronics, however, their smaller responses to external field inhibit device application. Recently the noncoll...
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Chapter and Conference Paper
Estimation of Friction Coefficient Between Outside Wheel Flange and Rail Considering Influence of Wheel/Rail Wear
The running safety of a railway vehicle against flange-climb derailment is evaluated with the derailment coefficient. A monitoring bogie, which can measure the derailment coefficient during commercial operatio...
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Article
Open AccessUltrafast thermal-free photoluminescence of coherently extended single quantum states
The coherent volume of single quantum states of matter is typically smaller than that of photons by several orders of magnitude, and hence, interactions between photons and single quantum states are normally v...
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Article
Prodigiosin R2, a new prodigiosin from the roseophilin producer Streptomyces griseoviridis 2464-S5
Roseophilin (2) is a unique prodigiosin-related compound produced by Streptomyces griseoviridis 2464-S5, and is characterized by a central furan ring and a bicyclic alkyl chain. During a search for biosynthetic i...
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Article
Diagnostic accuracy of late iodine enhancement on cardiac computed tomography with a denoise filter for the evaluation of myocardial infarction
We evaluated the image quality and diagnostic performance of late iodine enhancement (LIE) in dual-source computed tomography (DSCT) with low kilo-voltage peak (kVp) images and a denoise filter for the detecti...
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Article
Electric field dependence of the mode I energy release rate in single-edge cracked piezoelectric ceramics: effect due to polarization switching/dielectric breakdown
This study presents the results of the mode I energy release rate of a rectangular piezoelectric material with a single-edge crack under electromechanical loading. A crack was created normal or parallel to the...
