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    IgG4-related disease initially presented as an orbital mass lesion mimicking optic nerve sheath meningioma

    We report a case of an optic nerve mass lesion associated with IgG4-related disease. A 39-year-old man presented with right blurred vision and proptosis 8 years before admission. Magnetic resonance imaging sho...

    Shouhei Noshiro, Masahiko Wanibuchi, Yukinori Akiyama in Brain Tumor Pathology (2015)

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    Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells

    Mitochondrial autophagy eliminates damaged mitochondria and decreases reactive oxygen species (ROS). The autophagy inhibitor chloroquine (CQ) potentiates temozolomide (TMZ) cytotoxicity in glioma cells, but it...

    Yusuke S. Hori, Ryusuke Hosoda, Yukinori Akiyama, Rio Sebori in Journal of Neuro-Oncology (2015)

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    Primary central nervous system anaplastic large-cell lymphoma mimicking lymphomatosis cerebri

    Primary central nervous system lymphoma (PCNSL) is usually diffuse large B-cell lymphoma. Anaplastic large-cell lymphoma (ALCL) rarely occurs in the central nervous system. PCNSL always presents as single or m...

    Toshiya Sugino, Takeshi Mikami, Yukinori Akiyama in Brain Tumor Pathology (2013)