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Article
Immune checkpoint inhibitor-induced Trousseau syndrome: a case report
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Chapter and Conference Paper
Measurement and Analysis of the Strength Differential Effect of 5000 Series Aluminum Alloy Sheet
Tension-Compression Asymmetry (TCA) of a 1.5-mm-thick 5000-series aluminum alloy sheet, A5083-O, is measured using a uniaxial tensile test and in-plane compression test. In particular, the TCA observed for ann...
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Article
Open AccessProphylactic effects of isomaltodextrin in a Balb/c mouse model of egg allergy
The aim of this study was to evaluate the potential effects of isomaltodextrin (IMD), a dietary saccharide polymer derived from enzymatically produced from starch, on the ability to alter immune response (IR) ...
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Article
Open AccessBioaccumulation Patterns of Perfluoroalkyl Acids in an Estuary of the Ariake Sea, Japan
To evaluate the bioaccumulation potential of perfluoroalkyl acids (PFAAs) in an aquatic food web, we measured the concentrations of nine PFAAs in the water and aquatic organisms from an estuary of the Omuta Ri...
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Article
Open AccessRespiratory Uptake and Depuration Kinetics of Perfluorooctanesulfonate (PFOS) in a Marine Sandworm Species
We determined the respiratory uptake and depuration kinetics of perfluorooctanesulfonate (PFOS) in Perinereis wilsoni, a polychaete sandworm used as a model species to investigate the fate of chemical pollutants ...
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Article
Open AccessA longitudinal genome-wide association study of anti-tumor necrosis factor response among Japanese patients with rheumatoid arthritis
Studies of Caucasian patients with rheumatoid arthritis (RA) to identify genetic biomarkers of anti-tumor necrosis factor (TNF) response have used response at a single time point as the phenotype with which si...
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Article
Cardiac sympathetic function in the patients with amyotrophic lateral sclerosis: analysis using cardiac [123I] MIBG scintigraphy
Amyotrophic lateral sclerosis (ALS), which is the most serious form of degenerative motor neuron disease in adults, is characterized by upper and lower motor neuron degeneration, skeletal muscle atrophy, paral...
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Article
Is there a difference in gastric emptying between myotonic dystrophy type 1 patients with and without gastrointestinal symptoms?
Gastrointestinal symptoms are frequent complaints in patients with myotonic dystrophy type 1 (MyD1) and may be associated with reduced gastrointestinal motility caused by smooth muscle dysfunction. Although pr...
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Article
Open AccessCorticosteroid therapy in a patient with cerebral amyloid angiopathy-related inflammation
We studied longitudinal changes of the levels of anti-amyloid β (anti-Aβ) antibody, amyloid β (Aβ) protein, and interleukin 8 (IL-8) in cerebrospinal fluid (CSF) of a patient with cerebral amyloid angiopathy-r...
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Article
Long-term follow-up of nipple-sparing mastectomy without radiotherapy: a single center study at a Japanese institution
Recent reports have suggested that nipple-sparing mastectomy (NSM) is a potential alternative to mastectomy (MT). The aim of our study was to investigate the oncological and technical outcomes of NSM compared ...
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Article
Is there delayed gastric emptying in patients with multiple system atrophy? An analysis using the 13C-acetate breath test
Autonomic failure is one of the criteria according to the second consensus statement for the diagnosis of multiple system atrophy (MSA). Gastrointestinal symptoms are frequent complaints in patients with MSA a...
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Article
Is there a delayed gastric emptying of patients with early-stage, untreated Parkinson’s disease? An analysis using the 13C-acetate breath test
During the pre-symptomatic stage of Parkinson’s disease (PD), the idiopathic PD related abnormal synuclein immunostaining is confined to the medulla oblongata and olfactory bulb, according to Braak. In the stu...
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Article
Motor-dominant chronic inflammatory demyelinating polyneuropathy
We reviewed the clinical, electrophysiological an laboratory findings, plus the therapeutics and evolution of patients with motor-dominant Chronic inflammatory demyelinating polyneuropathy (CIDP) and compared ...
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Article
Probabilistic estimation of dietary exposure of the general Japanese population to dioxins in fish, using region-specific fish monitoring data
Many studies show that dietary consumption of fish is the greatest contributor to dioxin exposure of humans in Japan. To establish a link between ocean contamination and human exposure to dioxins in fish, we p...
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Article
Calcitonin Receptor Gene and Breast Cancer: Quantitative Analysis with Laser Capture Microdissection
There is a growing body of evidence indicating that calcitonin (CT) and its receptor (CTR) is involved in cell growth, differentiation and tissue development. Using laser capture microdissection (LCM) and real...
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Article
Magnetic resonance axillography for preoperative diagnosis of the axillopectoral muscle (langer’s axillary arch): a case report
The axillary arch of Langer is the most common muscular variation in the axilla. Recognition of anatomic variations is important for surgeons to perform safe axillary surgery. We describe a case of a woman wit...
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Article
Anastrozole-Induced remission of diaphragmatic paralysis from metastatic breast cancer treated with multiple prior therapies
We describe a woman with metastatic breast cancer treated with multiple rounds of prior cytotoxic and endocrine therapies, who presented with ipsilateral diaphragmatic paralysis. The use of anastrozole, a high...
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Article
Retinoid, Retinoic Acid Receptor β and Breast Cancer
Retinoids have been reported to inhibit the growth of several breast cancer cell lines in culture and to reduce breast tumor growth in animal models. Furthermore, retinoic acid (RA) can augment the action of o...
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Article
P63 expression in normal, hyperplastic and malignant breast tissues
p63 is a homologue of the p53 tumor suppressor gene and its protein is selectively expressed in the basal cells of a variety of epithelial tissues. It has recently been confirmed that p63 is expressed in the b...
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Article
Thymidine phosphorylase is regulated by tamoxifen in T47D breast cancer cell line
Thymidine phosphorylase (TP) has diverse functions within cells, including increasing the sensitivity of cancer cells to cytotoxic drugs including 5-fluorouracil (5-FU) and methotrexate. However, the regulator...