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Article
Open AccessDevelopment of extended pharmacokinetic models for propofol based on measured blood and brain concentrations
Propofol’s pharmacokinetics have been extensively studied using human blood samples and applied to target-controlled infusion systems; however, information on its concentration in the brain remains scarce. The...
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Article
Open AccessPre-stroke physical activity is associated with post-stroke physical activity and sedentary behavior in the acute phase
This study investigated the link between pre-stroke and acute-stage physical activity (PA) and sedentary behavior. Forty individuals with stroke (aged 73.6 ± 8.9 years) were enrolled. Post-stroke activity, inc...
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Article
Open AccessVisualization of heterogeneity and regional grading of gliomas by multiple features using magnetic resonance-based clustered images
Preoperative glioma grading is important for therapeutic strategies and influences prognosis. Intratumoral heterogeneity can cause an underestimation of grading because of the sampling error in biopsies. We de...