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Open Access5-Aminolevulinic acid antiviral efficacy against SARS-CoV-2 omicron variant in vitro
The coronavirus disease 2019 (COVID 19) pandemic continues to pose a threat to global health. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant (B.1.1.529) has spread rapidly wor...
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Article
Open AccessAntiviral activity of 5-aminolevulinic acid against variants of severe acute respiratory syndrome coronavirus 2
Genetic variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began to emerge in 2020 and have been spreading globally during the coronavirus disease 2019 (COVID-19) pandemic. Despite the pr...
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Article
Open AccessPlasmodium falciparum multidrug resistance gene-1 polymorphisms in Northern Nigeria: implications for the continued use of artemether-lumefantrine in the region
The analysis of single nucleotide polymorphism (SNPs) in drug-resistance associated genes is a commonly used strategy for the surveillance of anti-malarial drug resistance in populations of parasites. The pres...
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Article
Open AccessTheileria parasites subvert E2F signaling to stimulate leukocyte proliferation
Intracellular pathogens have evolved intricate mechanisms to subvert host cell signaling pathways and ensure their own propagation. A lineage of the protozoan parasite genus Theileria infects bovine leukocytes an...
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Article
Open AccessA Critical Role for Toxoplasma gondii Vacuolar Protein Sorting VPS9 in Secretory Organelle Biogenesis and Host Infection
Accurate sorting of proteins to the three types of parasite-specific secretory organelles namely rhoptry, microneme and dense granule in Toxoplasma gondii is crucial for successful host cell invasion by this obli...
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Article
Assessment of skin penetration of third-stage larvae of Strongyloides ratti
Strongyloides stercoralis infection is caused by skin penetration of third-stage larvae (L3s). We studied skin penetration of L3s of Strongyloides ratti using an in vitro assay that has been used previously to st...