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  1. No Access

    Article

    Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19

    Gastrointestinal fungal dysbiosis is a hallmark of several diseases marked by systemic immune activation. Whether persistent pathobiont colonization during immune alterations and impaired gut barrier function ...

    Takato Kusakabe, Woan-Yu Lin, **-Gyu Cheong, Gagandeep Singh in Nature Immunology (2023)

  2. Article

    Author Correction: Immune regulation by fungal strain diversity in inflammatory bowel disease

    **n V. Li, Irina Leonardi, Gregory G. Putzel, Alexa Semon, William D. Fiers in Nature (2022)

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    Article

    Immune regulation by fungal strain diversity in inflammatory bowel disease

    The fungal microbiota (mycobiota) is an integral part of the complex multikingdom microbial community colonizing the mammalian gastrointestinal tract and has an important role in immune regulation16. Although ab...

    **n V. Li, Irina Leonardi, Gregory G. Putzel, Alexa Semon, William D. Fiers in Nature (2022)

  4. No Access

    Article

    Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn’s disease

    Secretory immunoglobulin A (sIgA) plays an important role in gut barrier protection by sha** the resident microbiota community, restricting the growth of bacterial pathogens and enhancing host protective imm...

    Itai Doron, Marissa Mesko, **n V. Li, Takato Kusakabe in Nature Microbiology (2021)

  5. Article

    Open Access

    RNA is an Adjuvanticity Mediator for the Lipid-Based Mucosal Adjuvant, Endocine

    Nasal vaccination has the potential to elicit systemic and mucosal immunity against pathogens. However, split and subunit vaccines lack potency at stimulating mucosal immunity, and an adjuvant is indispensable...

    Masayuki Hayashi, Taiki Aoshi, Koji Ozasa, Takato Kusakabe in Scientific Reports (2016)