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  1. Article

    Open Access

    Monitoring of anti-drug antibodies and disease-specific biomarkers in three patients from a Japanese Fabry family treated with enzyme replacement therapy

    We monitored anti-drug antibodies and disease-specific biomarkers in three patients with a nonsense mutation from a Japanese Fabry family treated with enzyme replacement therapy (ERT). In two male patients fro...

    Takao Kubota, Takahiro Tsukimura, Tomoko Shiga, Tadayasu Togawa in CEN Case Reports (2023)

  2. Article

    Open Access

    Usefulness of glycated albumin as a predictor of mortality in chronic hemodialysis patients with diabetes: a multi-center, prospective cohort study

    The association of glycated albumin (GA) with mortality is unclear in chronic hemodialysis patients with diabetes. We investigated the usefulness of GA by comparing it with hemoglobin A1c (HbA1c) in this patie...

    Ko Hanai, Makoto Akamatsu, Aki Fujimori, Harumichi Higashi in Renal Replacement Therapy (2020)

  3. No Access

    Article

    Relative abundance of Megamonas hypermegale and Butyrivibrio species decreased in the intestine and its possible association with the T cell aberration by metabolite alteration in patients with Behcet’s disease (210 characters)

    We have previously demonstrated that the phylum Actinobacteria, the family Lactobacillaceae, and the genus Bifidobacterium increased in relative abundance of gut microbiota in patients with Behcet’s disease (BD)....

    Jun Shimizu, Takao Kubota, Erika Takada, Kenji Takai in Clinical Rheumatology (2019)

  4. No Access

    Article

    Is it possible to define salvageable ischemic penumbra using semiquantitative rCBF levels derived from MR perfusion-weighted imaging?

    The purpose of this study was to test if magnetic resonance (MR) perfusion-weighted imaging (PWI) can reliably characterize the ischemic penumbra.

    Kentaro Akazawa, Kei Yamada, Shigenori Matsushima, Takao Kubota in Neuroradiology (2008)

  5. No Access

    Article

    Regional cerebral blood flow in Alzheimer’s disease: Comparison between short and long-term donepezil therapy

    Treatment with donepezil improves cognitive function of patients with Alzheimer’s disease (AD) when compared to a placebo-controlled group. The purpose of this study was to investigate changes in regional cere...

    Yo Ushuima, Chio Okuyama, Satoru Mori, Takao Kubota in Annals of Nuclear Medicine (2006)

  6. No Access

    Article

    Age-related changes in the hemodynamics of the femoral head as evaluated by early phase of bone scintigraphy

    The femoral head is reported to be in a markedly hypoemic state as compared with other tissues even under normal conditions, and it is therefore necessary to understand its hemodynamics to investigate the path...

    Hiroyuki Hamaguchi, Mikihiro Fujioka, Kenji A. Takahashi in Annals of Nuclear Medicine (2006)

  7. No Access

    Article

    Higher lesion conspicuity for SENSE dynamic MRI in detecting hypervascular hepatocellular carcinoma: analysis through the measurements of liver SNR and lesion–liver CNR comparison with conventional dynamic MRI

    The aim of our study was to compare the signal-to-noise ratio (SNR) of liver parenchyma and the contrast-to-noise ratio (CNR) of hypervascular hepatocellular carcinoma (HCC) between conventional and SENSE dyna...

    Osamu Tanaka, Hirotoshi Ito, Kei Yamada, Takao Kubota, Osamu Kizu in European Radiology (2005)

  8. No Access

    Article

    Pitfalls of FDG-PET for the diagnosis of osteoblastic bone metastases in patients with breast cancer

    The purpose of this study was to investigate the pitfalls of using 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) for the evaluation of osteoblastic bone metastases in patients with breas...

    Takako Nakai, Chio Okuyama, Takao Kubota in European Journal of Nuclear Medicine and M… (2005)

  9. No Access

    Article

    Do short-time SPECT images of bone scintigraphy improve the diagnostic value in the evaluation of solitary lesions in the thoracic spine in patients with extraskeletal malignancies?

    Single photon emission computed tomography (SPECT) images provide many details of the anatomical structure. Also about bone scintigraphy, there are many reports of the improvement of diagnosis by SPECT images....

    Kana Kobayashi, Chio Okuyama, Takao Kubota, Takako Nakai in Annals of Nuclear Medicine (2005)

  10. No Access

    Article

    Assessment of the solid-state gamma camera to depict axillary sentinel lymph nodes in breast cancer patients

    The solid-state gamma camera is now commercially available offering the advantages of a compact and portable system, currently used mainly in the cardiac region. We evaluate the ability of the solid-state gamm...

    Mariko Goto, Chio Okuyama, Takao Kubota, YO Ushuima in Annals of Nuclear Medicine (2005)

  11. No Access

    Article

    Diagnosis of Alzheimer’s disease using brain perfusion SPECT and MR imaging: which modality achieves better diagnostic accuracy?

    The purpose of this study was to compare the accuracy of MR imaging and brain perfusion single-photon emission tomography (SPECT) in diagnosing Alzheimer’s disease (AD).

    Takao Kubota, Yo Ushijima, Kei Yamada in European Journal of Nuclear Medicine and M… (2005)

  12. No Access

    Article

    FDG-PET in a case of multiple bone metastases of gastric cancer

    F-18 2-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) is useful for surveys to detect bone metastasis because of its greater specificity than bone scintigraphy. However, FDG-PET is also known t...

    Takako Nakai, Chio Okuyama, Takao Kubota, Yo Ushuima in Annals of Nuclear Medicine (2005)

  13. No Access

    Article

    Pattern of111in-chloride bone marrow scintigraphy in myelodysplastic syndrome; comparison with clinical characteristics

    111In-chloride bone marrow scintigraphy (bone marrow scintigraphy) was performed in patients with myelodysplastic syndrome (MDS), tracer accumulation was classified into patterns, and the...

    Takako Nakai, Chio Okuyama, Takao Kubota, Kana Kobayashi in Annals of Nuclear Medicine (2004)

  14. No Access

    Article

    Diagnosis: multiple bone metastases of hepatocelluar carcinoma

    Takao Kubota in Annals of Nuclear Medicine (2001)

  15. No Access

    Article

    Two cases of necrotizing crescentic glomerulonephritis with skin lesions

    Two cases of rapidly progressive glomerulonephritis (RPGN) with skin vasculitis-associated anti-neutrophil cytoplasmic antibody (ANCA) are examined. Both cases showed purpura on the lower legs on admission and...

    Hidekazu Moriya, Iwao Nakabayashi, Junichirou Nishiyama in Japanese Journal of Rheumatology (1998)