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Article
High-intensity focused ultrasound treatment for hepatocellular carcinoma
High-intensity focused ultrasound (HIFU) represents a method employing high-intensity ultrasound energy to induce thermal ablation of cancerous cells. Regarded as minimally invasive, HIFU treatment offers redu...
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Article
Open AccessLong-term endoscopic gastric mucosal changes up to 20 years after Helicobacter pylori eradication therapy
Helicobacter pylori eradication therapy reduces the risk of gastric cancer. However, it is unclear whether the severity of risk factors for gastric cancer such as atrophy and intestinal metaplasia are reduced aft...
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Article
Severe induction of aberrant DNA methylation by nodular gastritis in adults
Nodular gastritis (NG) is characterized by marked antral lymphoid follicle formation, and is a strong risk factor for diffuse-type gastric cancer in adults. However, it is unknown whether aberrant DNA methylat...
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Article
Prediction of the Severity of Gastrointestinal Bleeding: Reassessing Dominant Wisdom
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Article
Deep learning approach for discrimination of liver lesions using nine time-phase images of contrast-enhanced ultrasound
Contrast-enhanced ultrasound (CEUS) shows different enhancement patterns depending on the time after administration of the contrast agent. The aim of this study was to evaluate the diagnostic performance of li...
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Article
Open AccessEvidence-based clinical practice guidelines for cholelithiasis 2021
The Japanese Society of Gastroenterology first published evidence-based clinical practice guidelines for cholelithiasis in 2010, followed by a revision in 2016. Currently, the revised third edition was publish...
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Article
Open AccessVisibility of early gastric cancers by texture and color enhancement imaging using a high-definition ultrathin transnasal endoscope
We evaluated whether texture and color enhancement imaging (TXI) using a high-definition ultrathin transnasal endoscope (UTE) improves the visibility of early gastric cancer (EGC) compared with white-light ima...
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Article
Current status and future perspective of sonodynamic therapy for cancer
There is a tremendous need for prevention and effective treatment of cancer due to the associated morbidity and mortality. In this study, we introduce sonodynamic therapy (SDT), which is expected to be a new c...
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Article
Validation of the BEST-J score, a prediction model for bleeding after endoscopic submucosal dissection for early gastric cancer: a multicenter retrospective observational study
A new scoring system, the BEST-J score, using ten risk factors to assign cases to different post-endoscopic submucosal dissection (ESD) risk groups for bleeding, has been shown to be accurate for risk stratifi...
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Article
Open AccessExtensive gut virome variation and its associations with host and environmental factors in a population-level cohort
Indigenous bacteriophage communities (virome) in the human gut have a huge impact on the structure and function of gut bacterial communities (bacteriome), but virome variation at a population scale is not full...
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Article
Diagnostic efficacy of the Japan NBI Expert Team classification with dual-focus magnification for colorectal tumors
The Japan NBI Expert Team (JNET) classification is the first unified classification criteria for colorectal tumors using magnifying narrow-band imaging (NBI) in Japan. However, the diagnostic stratification ab...
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Article
Open AccessCorrection to: Clinical guidelines for primary sclerosing cholangitis 2017
The article “Clinical guidelines for primary sclerosing cholangitis 2017”, written by Hiroyuki Isayama, Susumu Tazuma, Norihiro Kokudo, Atsushi Tanaka, Toshio Tsuyuguchi, Takahiro Nakazawa, Kenji Notohara, Sug...
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Article
Open AccessHigh-intensity focused ultrasound therapy for pancreatic cancer
Pancreatic cancer (PC) has one of the poorest prognoses among solid cancers, and its incidence has increased recently. Satisfactory outcomes are not achieved with current therapies; thus, novel treatments are ...
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Article
Open AccessAmendment of the Japanese consensus guidelines for autoimmune pancreatitis, 2020
In response to the latest knowledge and the amendment of the Japanese diagnostic criteria for autoimmune pancreatitis (AIP) in 2018, the Japanese consensus guidelines for managing AIP in 2013 were required to...
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Chapter
Endoscopic Management of Peripancreatic Fluid Collection
Patients with acute necrotic pancreatitis occasionally develop walled-off necrosis (WON). Traditionally, surgical necrosectomy has been the standard treatment for symptomatic WON. However, open surgical necros...
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Chapter
EUS-Guided Balloon Occluded Gastrojejunostomy Bypass
Malignant gastric outlet obstruction (GOO) is often observed in patients with advanced pancreatobiliary and gastroduodenal cancers. In recent years, endoscopic ultrasonography-guided gastroenterostomy (EUS-GE)...
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Reference Work Entry In depth
EUS- and Enteroscopy-Assisted ERCP
Deep biliary cannulation, a process in endoscopic retrograde cholangiopancreatography (ERCP), requires immense technical skill. Furthermore, 100% biliary cannulation cannot be achieved even by skilled pancreat...
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Chapter
EUS-PD for Pancreaticojejunostomy Stricture
For patients with a surgically altered anatomy (SAA), such as for those who have undergone pancreaticoduodenectomy, pancreatic duct drainage by endoscopic retrograde cholangiopancreatography (ERCP) for pancrea...
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Article
The most appropriate region-of-interest position for attenuation coefficient measurement in the evaluation of liver steatosis
Attenuation imaging (ATI) is a new noninvasive ultrasound technique for assessing steatosis grade (S). However, validated region-of-interest (ROI) sampling strategies are not currently available. We investigat...
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Article
Elucidation of spleen elasticity and viscosity in a carbon tetrachloride rat model of liver cirrhosis using a new ultrasound elastography
Measurement of spleen stiffness (SS) using ultrasound (US) elastography is useful for predicting portal hypertension. However, the mechanism leading to increased SS remains unclear. We jointly developed a new ...
