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  1. No Access

    Article

    Feasibility study of direct fentanyl patch introduction without prior opioid titration

    Opioids are key drugs for cancer pain relief, but some patients, especially those who have gastroenterological cancers, suffer from severe opioid-induced bowel dysfunction (OBD), which reduces their quality of...

    Takanori Matsui, Taiki Kojima, Hiroshi Kojima… in International Journal of Clinical Oncology (2009)

  2. No Access

    Article

    Detection of K-ras mutations in the plasma DNA of pancreatic cancer patients

    In pancreatic cancers, K-ras mutations have been found frequently (80%–100%), and they could be a good marker to detect tumor DNA in the plasma. Several studies have indicated that polymerase chain reaction/restr...

    Takanori Uemura, Kenji Hibi, Tetsuya Kaneko, Shin Takeda… in Journal of Gastroenterology (2004)