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Article
Open AccessFactors associated with physical activity following total knee arthroplasty for knee osteoarthritis: a longitudinal study
After total knee arthroplasty (TKA), patients’ physical activity (PA) levels at 6 months are lower than those of healthy subjects. Few studies have investigated the factors associated with PA at 6 months after...
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Chapter and Conference Paper
Device Classification via Passive Fingerprints with Clustering Algorithm
In browser fingerprinting, device identification becomes increasingly difficult as the number of accesses increases because the number of combinations to be predicted increases exponentially. This paper propos...
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Article
Open AccessGenetic alterations that deregulate RB and PDGFRA signaling pathways drive tumor progression in IDH2-mutant astrocytoma
In IDH-mutant astrocytoma, IDH2 mutation is quite rare and biological mechanisms underlying tumor progression in IDH2-mutant astrocytoma remain elusive. Here, we report a unique case of IDH2 mutant astrocytoma, C...
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Article
Investigating the characteristics of fluorescence features on sweet peppers using UV light excitation
Sweet peppers are popular worldwide due to their nutrition and taste. Conventional vegetable tracing methods have been trialed, but the application of such labels or tags can be laborious and expensive, making...
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Article
C-reactive Protein Levels and Cardiovascular Outcomes After Febuxostat Treatment in Patients with Asymptomatic Hyperuricemia: Post-hoc Analysis of a Randomized Controlled Study
Inflammation plays an important role in the initiation and progression of atherosclerosis, leading to poor clinical outcomes. Hyperuricemia is associated with the activation of the Nod-like receptor protein 3 ...
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Article
Open AccessLeigh-like syndrome with progressive cerebellar atrophy caused by novel HIBCH variants
Pathogenic variants in the HIBCH gene cause HIBCH deficiency, leading to mitochondrial disorders associated with valine metabolism. Patients typically present with symptoms such as developmental regression/delay,...
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Article
Febuxostat and renal outcomes: post-hoc analysis of a randomized trial
Effect of urate-lowering on renal outcomes in patients at high-risk for cardiovascular disease with hyperuricemia without gout is not known. We conducted a post hoc analysis of a randomized trial (Febuxostat f...
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Article
Association of fear of falling with cognitive function and physical activity in older community-dwelling adults
To explore the association between fear of falling and physical activity independent of cognitive decline.
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Article
Impact of bleeding events after percutaneous coronary intervention in patients on hemodialysis
Coronary artery disease is common in patients on dialysis; there is a high rate of bleeding events after percutaneous coronary intervention (PCI) in such patients. We investigated the impact of bleeding events...
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Article
Open AccessBRAF V600E mutation mediates FDG-methionine uptake mismatch in polymorphous low-grade neuroepithelial tumor of the young
We present a case of a 14-year old boy with tumor-associated refractory epilepsy. Positron emission tomography imaging demonstrated a region with heterogeneous high 11C-methionine uptake and a region with homogen...
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Article
Open AccessRisk factors for cancer-associated thrombosis in patients undergoing treatment with immune checkpoint inhibitors
Purpose Anticancer agents are known to increase cancer-associated thrombosis (CAT) onset. CAT onset rate is reported to be 1.92% in cisplatin-based therapy, 6.1% in paclitaxel plus ramucirumab combination therapy...
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Article
Open AccessCorrelation between immune-related adverse events and prognosis in patients with various cancers treated with anti PD-1 antibody
Immune checkpoint inhibitors (ICIs) targeting programmed cell death protein 1 (PD-1) are used for the treatment of various cancer types. However, immune-related adverse events (irAEs) occur in patients treated...
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Chapter
Falls and Related Bone Fractures
According to the 2016 Vital Statistics of Japan, 8030 people die from falling each year, 88% of whom are 65 years and older [1]. The primary cause of functional disability is a bone fracture in 12% of the case...
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Article
Open AccessRepeat hepatectomy with systemic chemotherapy might improve survival of recurrent liver metastasis from colorectal cancer—a retrospective observational study
Although hepatectomy for metastatic colorectal cancer (mCRC) prolongs survival in up to 40% of people, recurrence rates approach 70%. We used a multidisciplinary approach to treat recurrent liver metastases, i...
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Chapter and Conference Paper
Development of a Tour Recommendation System Using Online Customer Reviews
In this paper, we propose a system for recommending tours using online customer reviews. The system receives a review about tours written by a user, estimates the user’s interests about tours from the review, ...
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Article
Capture and characterization of a reactive haem–carbenoid complex in an artificial metalloenzyme
Non-canonical amino acid ligands are useful for fine-tuning the catalytic properties of metalloenzymes. Here, we show that recombinant replacement of the histidine ligand proximal to haem in myoglobin with Nδ-met...
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Chapter and Conference Paper
Discrimination of Personal Opinions from Commercial Speech Based on Subjectivity of Text
This paper presents a method for discriminating personal opinions from commercial speech. Today many personal opinions such as complaints about a particular product can be found on the Web. Mining useful infor...
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Article
Open AccessComparison between hypersensitivity reactions to cycles of modified FOLFOX6 and XELOX therapies in patients with colorectal cancer
Although hypersensitivity reactions (HSRs) to oxaliplatin (L-OHP) therapy are well-documented, few reports have compared different therapies in terms of HSR occurrence. In this study, we compared the frequency...
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Article
Prognostic role of the combination of platelet count and neutrophil–lymphocyte ratio in patients with hypopharyngeal squamous cell carcinoma
Hypopharyngeal squamous cell carcinoma (HPSCC) is an aggressive disease with poor prognosis; but has no established biomarkers on the order of human papilloma virus and p16 in oropharyngeal carcinoma. This stu...
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Article
Open AccessEvaluation of a method for calculating carboplatin dosage in DeVIC ± R therapy (combination therapy of dexamethasone, etoposide, ifosfamide and carboplatin with or without rituximab) as a salvage therapy in patients with relapsed or refractory non-Hodgkin lymphoma
Several studies have evaluated the utility of extrapolating the Calvert formula in calculating carboplatin (CBDCA) dosages in solid tumours; however, data regarding haematological cancers are less. Therefore, ...
