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Article
A comparison between stand-alone left atrial appendage occlusion and resection as a method of preventing cardiogenic thromboembolic stroke
The present study evaluated the differences between left atrial appendage occlusion (LAAO) and left atrial appendage resection (LAAR) in terms of the safety and efficacy.
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Article
Open AccessCharacterization of CD90/Thy-1 as a crucial molecular signature for myogenic differentiation in human urine-derived cells through single-cell RNA sequencing
Human urine-derived cells (UDCs) are primary cultured cells originating from the upper urinary tract and are known to be multipotent. We previously developed MYOD1-transduced UDCs (MYOD1-UDCs) as a model recapitu...
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Article
Open AccessInvolvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons
Cyclin-dependent kinase 5 (Cdk5) /p35 is involved in many developmental processes of the central nervous system. Cdk5/p35 is also implicated in synaptic plasticity, learning and memory. Several lines of condit...
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Article
Open AccessLateralization of CA1 assemblies in the absence of CA3 input
In the hippocampal circuit CA3 input plays a critical role in the organization of CA1 population activity, both during learning and sleep. While integrated spatial representations have been observed across the...
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Article
Open AccessTraceable stimulus-dependent rapid molecular changes in dendritic spines in the brain
Dendritic spines function as microcompartments that can modify the efficiency of their associated synapses. Here, we analyzed stimulus-dependent molecular changes in spines. The F-actin cap** protein CapZ ac...
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Chapter and Conference Paper
Longest Square Subsequence Problem Revisited
The longest square subsequence (LSS) problem consists of computing a longest subsequence of a given string S that is a square, i.e., a longest subsequence of form XX appearing in S. It is known that an LSS of a s...
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Protocol
Synaptic Function and Neuropathological Disease Revealed by Quantum Dot-Single-Particle Tracking
Quantum dot-single-particle tracking (QD-SPT) is a super-resolution imaging technique that uses semiconductor nanocrystal quantum dots as fluorescent probes and is a powerful tool for analyzing protein and lip...
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Article
Open AccessSpinal epidural abscess caused by Pasteurella multocida mimicking aortic dissection: a case report
Pasteurella multocida (P. multocida) forms part of the normal flora of many animals. Although it is a common causative agent of skin and soft tissue infection after an animal bite or scratch, in rare cases it can...
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Article
Open AccessAstrocytic endfeet re-cover blood vessels after removal by laser ablation
The astrocyte, one of the glial cells, plays many functional roles. These include provision of nutrients from blood vessels to neurons, supply of neurotransmitters and support of blood–brain barrier (BBB) inte...
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Article
Analysis of the perioperative change in cognitive function of patients with risk factors for cognitive impairment in cardiovascular surgery
The purpose of the present study is to assess the perioperative changes in the cognitive function of patients after cardiovascular surgery (CVS) and to find out risk factors for early postoperative cognitive d...
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Article
Thoracoscopic left atrial appendectomy and thoracic endovascular aortic repair (TEVAR) in a patient with cardiogenic stroke combined with acute aortic dissection
The simultaneous occurrence of cardiogenic stroke and acute aortic dissection is rare, and its treatment remains unclear. Although anticoagulation therapy is usually chosen for cardiogenic stroke due to atrial...
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Article
Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity
Keratinocytes undergo a unique type of programmed cell death known as cornification, which leads to the formation of the stratum corneum (SC), the main physical barrier of the epidermis. A defective epidermal ...
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Article
Efficacy of vacuum-assisted closure therapy on rehabilitation during the treatment for surgical site infection after cardiovascular surgery
Surgical site infection (SSI) after cardiovascular procedures is a severe complication, potentially leading to high morbidity and mortality. In addition, during the treatment of SSI, rehabilitation is delayed,...
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Article
Open AccessCorrection: Corrigendum: Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders
Nature Communications 7: Article number:10594 (2016); Published: 03 February 2016; Updated: 20 April 2016 Previous work by Rosário et al. 2007 and Schuster et al. 2015 describing the role of ARHGAP33 in regula...
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Article
Open AccessEmerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders
Intracellular trafficking of receptor proteins is essential for neurons to detect various extracellular factors during the formation and refinement of neural circuits. However, the precise mechanisms underlyin...
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Article
Four-year paracorporeal left ventricular assist device (LVAD) support for heart failure after Rastelli operation
It is well known that heart failure can occur after a conventional Rastelli operation (using an anatomical right ventricle as a systemic ventricle) in patients with congenitally corrected transposition of the ...
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Article
Chemically inducible diffusion trap at cilia reveals molecular sieve–like barrier
Chemically inducible diffusion trap at cilia (CIDTc), a method to trap proteins in the cilia, was applied to study the kinetics of protein accumulation and reveal a molecular sieve at the ciliary base. CIDTc c...
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Article
Laterality of cervical disc herniation
Cervical disc herniation (CDH) is found more frequently at the lower cervical spine than at the upper or middle level. However, there is scarcity of data about the laterality of CDH. The aim of this study is t...
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Article
Left ventricular assist device support with a centrifugal pump for 2 months in a 5-kg child
The mid-term and long-term results of left ventricular assist device (LVAD) implantation for small children are still unsatisfactory. There have been few reports of LVAD implantation for more than a month in c...
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Article
Aboveground productivity of an unsuccessful 140-year-old Cryptomeria japonica plantation in northern Kyushu, Japan
We measured the aboveground biomass, biomass increment and litterfall production of a 140-year-old, abandoned Cryptomeria japonica plantation in order to infer the effects of topography on biomass production. The...
