18 Result(s)

Article

Trends in allogeneic hematopoietic cell transplantation survival using population-based descriptive epidemiology method: analysis of national transplant registry data

Prognosis for patients undergoing hematopoietic cell transplantation (HCT) has been improving. Short-term survival information, such as crude survival rates that consider deaths immediately after the transplan...

Yachiyo Kuwatsuka, Hidemi Ito, Ken Tabuchi, Takaaki Konuma… in Bone Marrow Transplantation (2024)

Article

Donor NKG2D rs1049174 polymorphism predicts hematopoietic recovery and event-free survival after single-unit cord blood transplantation in adults

Takaaki Konuma, Megumi Hamatani-Asakura, Maki Monna-Oiwa… in Bone Marrow Transplantation (2024)

Article

The effect of center experience on allogeneic hematopoietic cell transplantation outcomes in acute myeloid leukemia

This study aimed to address the prognostic impact of center experience based on the data of 7821 adults with acute myeloid leukemia who underwent allogeneic hematopoietic cell transplantation (HCT) from 2010 t...

Masamitsu Yanada, Shingo Yano, Yachiyo Kuwatsuka… in Bone Marrow Transplantation (2024)

Article

External validation and extended application of the transplant conditioning intensity score in acute myeloid leukemia

This study aimed to validate the utility of the transplant conditioning intensity (TCI) score in 1714 patients with acute myeloid leukemia (AML) undergoing allogeneic bone marrow or peripheral blood stem cell ...

Masamitsu Yanada, Yoshimitsu Shimomura, Shohei Mizuno… in Bone Marrow Transplantation (2023)

Article

Salvage single-unit unrelated cord blood transplantation for graft failure following initial allogeneic transplantation in adult acute myeloid leukemia: trends in outcomes over the past 20 years

Takaaki Konuma, Kaito Harada, Tadakazu Kondo… in Bone Marrow Transplantation (2022)

Article

Outcomes of third allogeneic hematopoietic stem cell transplantation in relapsed/refractory acute leukemia after a second transplantation

Relapsed acute leukemia after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is associated with poor prognosis. In a subset of patients, durable remissions can be achieved with a second allo-HS...

Shinichi Kobayashi, Yoshinobu Kanda, Takaaki Konuma… in Bone Marrow Transplantation (2022)

Article

Cord blood index predicts engraftment and early non-relapse mortality in adult patients with single-unit cord blood transplantation

How to select optimal cord blood (CB) remains an important clinical question. We developed and validated an index of CB engraftment, the cord blood index (CBI), which uses three weighted variables representing...

Gaku Kondo, Fumihiko Ishimaru, Takaaki Konuma… in Bone Marrow Transplantation (2021)

Article

Prognostic value of measurable residual disease at allogeneic transplantation for adults with core binding factor acute myeloid leukemia in complete remission

Pretransplant measurable residual disease (MRD) has been shown to be associated with relapse incidence following allogeneic hematopoietic cell transplantation (HCT) for acute myeloid leukemia (AML). However, i...

Takaaki Konuma, Tadakazu Kondo, Masayoshi Masuko… in Bone Marrow Transplantation (2021)

Article

Allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome in adolescent and young adult patients

Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curable treatment option for adolescent and young adult (AYA) patients with myelodysplastic syndrome (MDS). The study aim was to evaluate e...

Yoshimitsu Shimomura, Masahiko Hara, Takaaki Konuma… in Bone Marrow Transplantation (2021)

Article

Relapse of acute myeloid leukemia after allogeneic hematopoietic cell transplantation: clinical features and outcomes

Posttransplant relapse represents the greatest obstacle to the success of allogeneic hematopoietic cell transplantation (HCT) for patients with acute myeloid leukemia (AML). This study investigated clinical fe...

Masamitsu Yanada, Takaaki Konuma, Satoshi Yamasaki… in Bone Marrow Transplantation (2021)

Article

Predicting non-relapse mortality following allogeneic hematopoietic cell transplantation during first remission of acute myeloid leukemia

The aim of this study was to develop a comprehensive system for predicting non-relapse mortality after allogeneic hematopoietic cell transplantation (HCT) during first complete remission (CR) of acute myeloid ...

Masamitsu Yanada, Takaaki Konuma, Shohei Mizuno… in Bone Marrow Transplantation (2021)

Article

Early fluid overload predicts higher non-relapse and overall mortality in adults after single-unit cord blood transplantation

Early fluid overload has been associated with poor transplant outcomes after allogeneic hematopoietic cell transplantation. However, its effects on the outcomes after cord blood transplantation (CBT) are uncle...

Takaaki Konuma, Maki Oiwa-Monna, Mai Mizusawa… in Bone Marrow Transplantation (2019)

Article

Red blood cell transfusion burden by day 30 predicts mortality in adults after single-unit cord blood transplantation

Increased red blood cell (RBC) transfusion requirements are associated with morbidity and mortality after allogeneic hematopoietic cell transplantation. However, its impact on the outcomes after cord blood tra...

Takaaki Konuma, Maki Oiwa-Monna, Mai Mizusawa… in Bone Marrow Transplantation (2019)

Article

Unit selection for umbilical cord blood transplantation for adults with acute myeloid leukemia in complete remission: a Japanese experience

To investigate optimal unit selection for umbilical cord blood transplantation (UCBT), we conducted a registry-based study of 1355 adults with acute myeloid leukemia in first or second complete remission who u...

Masamitsu Yanada, Takaaki Konuma, Yachiyo Kuwatsuka… in Bone Marrow Transplantation (2019)

Article

Circulating monocyte subsets in human chronic graft-versus-host disease

Chronic graft-versus-host disease (cGVHD) is a major cause of late morbidity and mortality after allogeneic hematopoietic cell transplantation (HCT). Monocytes/macrophages play a central role in inflammation, ...

Takaaki Konuma, Chisato Kohara, Eri Watanabe… in Bone Marrow Transplantation (2018)

Article

Does marital status affect the outcomes after allogeneic hematopoietic cell transplantation?

Tomoko Sato, Takaaki Konuma, Maki Oiwa-Monna, Susumu Tanoue… in Bone Marrow Transplantation (2018)