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Article
Development of plasma sources and diagnostics for the simulation of fusion edge plasmas
Although the research on divertors and scrape-off layers (SOLs) has been not as focused on as the recent success of the Korean fusion program, a few linear plasma devices have been developed for simulating div...
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Article
p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain)
Recurrent cytogenetic abnormalities are the main hallmark of multiple myeloma (MM) and patients having 2 or more high-risk prognostic events are associated with extremely poor outcome. 17p13(del) and 1q21(gain...
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Article
Open AccessGenomic characterization of functional high-risk multiple myeloma patients
Multiple myeloma (MM) patients with suboptimal response to induction therapy or early relapse, classified as the functional high-risk (FHR) patients, have been shown to have poor outcomes. We evaluated newly-d...
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Article
Open AccessMyeloma-specific superenhancers affect genes of biological and clinical relevance in myeloma
Multiple myeloma (MM) is an aggressive plasma cell neoplasm characterized by genomic heterogeneity. Superenhancers (SEs) are defined as large clusters of enhancers in close genomic proximity, which regulate ge...
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Article
Lymphocyte cytosolic protein 1 (LCP1) is a novel TRAF3 dysregulation biomarker with potential prognostic value in multiple myeloma
Chromosomal rearrangement involving 14q32 region that results in TNF receptor associated factor 3 (TRAF3) dysfunctional mutation is the most frequent NF-κB pathway mutation in multiple myeloma (MM). Subsequent...
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Article
Open AccessFrequent upregulation of G9a promotes RelB-dependent proliferation and survival in multiple myeloma
Multiple myeloma is an incurable hematological malignancy characterized by a heterogeneous genetic and epigenetic landscape. Although a number of genetic aberrations associated with myeloma pathogenesis, progr...
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Article
Open AccessA discrete core-shell-like micro-light-emitting diode array grown on sapphire nano-membranes
A discrete core-shell-like micro-light-emitting diode (micro-LED) array was grown on a 100 nm-thick sapphire nano-membrane array without harmful plasma etching for chip singulation. Due to proper design for th...
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Chapter
Applications of Microarray in Cancer Cell Signaling Pathways
Microarrays allow for the analysis of transcription in a large number of genes simultaneously. They have played an important role in the identification of cancer cell signaling pathways. The ease of use and re...
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Article
Open AccessFlower-Like Internal Emission Distribution of LEDs with Monolithic Integration of InGaN-based Quantum Wells Emitting Narrow Blue, Green, and Red Spectra
We report a phosphor-free white light-emitting diodes (LED) realized by the monolithic integration of In0.18Ga0.82N/GaN (438 nm, blue), In0.26Ga0.74N/GaN (513 nm, green), and In0.45Ga0.55N/In0.13Ga0.87N (602 nm, ...
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Article
Improvement of device performances, including electrostatic discharge characteristics, of InGaN/GaN light-emitting diodes by using a Si-doped graded superlattice
We report the influences of a Si-doped graded-superlattice (SiGSL) on the structural, optical, and electrical properties of InGaN/GaN light-emitting diodes (LEDs). For comparison, LEDs fabricated on an undoped...
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Article
Open AccessInvestigating carrier localization and transfer in InGaN/GaN quantum wells with V-pits using near-field scanning optical microscopy and correlation analysis
The V-pits and potential fluctuations in InGaN/GaN multiple quantum wells (MQWs) are key factors for understanding the performance of InGaN/GaN-based light-emitting diodes (LEDs). However, photoluminescence (P...
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Article
Open AccessRecent progress in toxicogenomics research in South Korea
The importance of toxicogenomics was recognized early in Korea and a group of researchers was trying to build up a research infrastructure and educational system. However, since the scale of the Korean pharmac...
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Article
Open AccessHigh-resolution analysis of condition-specific regulatory modules in Saccharomyces cerevisiae
We present an approach for identifying condition-specific regulatory modules by using separate units of gene expression profiles along with ChIP-chip and motif data from Saccharomyces cerevisiae. By investigating...
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Chapter and Conference Paper
An Open Source Microarray Data Analysis System with GUI: Quintet
We address Quintet, an R-based unified cDNA microarray data analysis system with GUI. Five principal categories of microarray data analysis have been coherently integrated in Quintet: data processing steps suc...
