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  1. Article

    Open Access

    Epithelial cell-derived cytokine TSLP activates regulatory T cells by enhancing fatty acid uptake

    Epithelial cells control a variety of immune cells by secreting cytokines to maintain tissue homeostasis on mucosal surfaces. Regulatory T (Treg) cells are essential for immune homeostasis and for preventing t...

    Tadamichi Kasuya, Shigeru Tanaka, Jun Tamura, Keishi Etori in Scientific Reports (2023)

  2. Article

    Open Access

    Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium

    Methotrexate (MTX) is an anchor drug for the treatment of rheumatoid arthritis (RA). However, the precise mechanisms by which MTX stalls RA progression and alleviates the ensuing disease effects remain unknown...

    Jumpei Shoda, Shigeru Tanaka, Keishi Etori, Koto Hattori in Arthritis Research & Therapy (2022)