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Open AccessPitting Corrosion in 316L Stainless Steel Fabricated by Laser Powder Bed Fusion Additive Manufacturing: A Review and Perspective
316L stainless steel (316L SS) is a flagship material for structural applications in corrosive environments, having been extensively studied for decades for its favorable balance between mechanical and corrosi...
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Article
Open AccessFramework Implementation of the INSPIRE ICOPE-CARE Program in Collaboration with the World Health Organization (WHO) in the Occitania Region
Limiting the number of dependent older people in coming years will be a major economic and human challenge. In response, the World Health Organization (WHO) has developed the «Integrated Care for Older People ...
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Cognitive and functional patterns of nondemented subjects with equivocal visual amyloid PET findings
Despite good to excellent inter-reader agreement in the evaluation of amyloid load on PET scans in subjects with Alzheimer's disease, some equivocal findings have been reported in the literature. We aimed to d...
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Article
La télémédecine : une nouvelle pratique en médecine générale pour la prise en charge non médicamenteuse des troubles du comportement du patient dément
En France, la Haute Autorité de santé (HAS) préconise de privilégier les prescriptions non médicamenteuses pour la prise en charge des troubles du comportement du patient dément. La consultation traditionnelle...
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Amyloid imaging in Alzheimer’s disease: A literature review
Therapies targeting amyloid-β peptide currently represent approximately 50% of drugs now being developed for Alzheimer’s disease. Some, including active and passive anti-Aβ immunotherapy, directly target the a...
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Troubles psychologiques de la fragilité
Le syndrome de fragilité traduit la diminution des réserves fonctionnelles d’un individu âgé, limitant ses capacités d’adaptation face à un événement ou un stress même mineur dans une histoire de vie. Ceci l’e...
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Place des unités cognitivo-comportementales (UCC) dans la prise en charge de la maladie d’Alzheimer
Dans l’évolution de la maladie d’Alzheimer peuvent survenir des périodes de crises, d’origine multifactorielle (fatigue de l’aidant, maladies aiguës, rupture de la prise en charge…), qui peuvent se traduire pa...
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Comment prévenir la « dépendance iatrogène » lors de l’hospitalisation d’un patient atteint de la maladie d’Alzheimer?
Parmi les sujets âgés hospitalisés dans les services de soins aigus, 20 à 40 % ont une démence déjà diagnostiquée [1], qu’il s’agisse d’une maladie d’Alzheimer ou d’une démence apparentée. À comorbidité égale,...
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Article
Open AccessUsing PET with 18F-AV-45 (florbetapir) to quantify brain amyloid load in a clinical environment
Positron emission tomography (PET) imaging of brain amyloid load has been suggested as a core biomarker for Alzheimer’s disease (AD). The aim of this study was to test the feasibility of using PET imaging with 18
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Comment réduire la dépendance iatrogène chez les sujets âgés hospitalisés ?
L’hospitalisation représente la première cause de déclin fonctionnel chez les personnes âgées; 30 à 60% d’entre elles perdent de l’autonomie sur les activités de base de la vie quotidienne (AVQ). Cette perte d...
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Article
Rapid cognitive decline, one-year institutional admission and one-year mortality: Analysis of the ability to predict and inter-tool agreement of four validated clinical frailty indexes in the safes cohort
To evaluate the predictive ability of four clinical frailty indexes as regards one-year rapid cognitive decline (RCD — defined as the loss of at least 3 points on the MMSE score), and one-year institutional ad...
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Article
Reducing “iatrogenic disability” in the hospitalized frail elderly
Hospitalization is the first cause of functional decline in the elderly: 30 to 60% of elderly patients lose some independence in basic activities of daily living (ADL) during a stay in hospital. This loss of i...
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Article
Predictors of institution admission in the year following acute hospitalisation of elderly people
The aim of the study was to identify factors related to institutionalisation within one-year follow up of subjects aged 75 or over, hospitalised via the emergency department (ED).
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Prévention, dépistage et prise en charge thérapeutique du syndrome confusionnel
L’évaluation clinique et la détection du syndrome confusionnel chez la personne âgée est une tâche complexe qui présente un défi de taille pour les professionnels de santé. Le syndrome confusionnel est en effe...
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Article
Predictive factors of hospitalizations in Alzheimer’s disease: A two-year prospective study in 686 patients of the REAL.FR study
During the course of the Alzheimer’s disease (AD), many patients need to be hospitalized either due to the direct consequences of the disease itself, or due to associated diseases or life event. The objective ...
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Descriptive analysis of hospitalizations of patients with Alzheimer’s disease: A two-year prospective study of 686 patients from the REAL.FR study
There is lack of data on the frequency and the causes of hospitalization in mild to moderate Alzheimer’s disease (AD) patients. The aims of the present study were to evaluate the frequency and the causes of ho...
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Article
Mild Alzheimer’s disease: A «Position Paper»
Under the auspices of the Société Française de Gériatrie et Gérontologie, a multi-disciplinary group of specialists in geriatrics, neurology, epidemiology, psychiatry, neuroradiology and nuclear medicine met w...
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Diagnostic précoce de la maladie d’Alzheimer
Le retard diagnostique en France de la maladie d’Alzheimer nécessite la mise en place d’une démarche permettant un diagnostic plus précoce. Cependant, le diagnostic au stade léger reste difficile, et l’émergen...
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Troubles cognitifs et hallucinations visuelles tardives chez un homme de 70 ans
M. C., droitier, ingénieur à la retraite, consulte pour la première fois à l’age de 65 ans pour une plainte mnésique. Les troubles semblent d’installation progressive. L’examen neurologique était alors sans pa...
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Derivation and validation of a mortality-risk index from a cohort of frail elderly patients hospitalised in medical wards via emergencies: the SAFES study
To identify predictive factors for 2-year mortality in frail elderly patients after acute hospitalisation, and from these to derive and validate a Mortality Risk Index (MRI). A prospective cohort of elderly pa...