13 Result(s)

Article

Real-world treatment patterns and outcomes of abemaciclib for the treatment of HR + , HER2- metastatic breast cancer patients in Japan

This study described, in routine clinical practice in Japan, the patient characteristics, treatment patterns, and outcomes of female patients with HR + /HER2- metastatic breast cancer (MBC) who started abemaci...

K. Nozawa, M. Terada, M. Onishi, Y. Ozaki, T. Takano, W. Fakhouri… in Breast Cancer (2023)

Article

Efficacy and safety of trastuzumab, lapatinib, and paclitaxel neoadjuvant treatment with or without prolonged exposure to anti-HER2 therapy, and with or without hormone therapy for HER2-positive primary breast cancer: a randomised, five-arm, multicentre, open-label phase II trial

Dual blockade of HER2 promises increased pathological complete response (pCR) rate compared with single blockade in the presence of chemotherapy for HER2-positive (+) primary breast cancer. Many questions rema...

N. Masuda, M. Toi, N. Yamamoto, H. Iwata, K. Kuroi, H. Bando, S. Ohtani… in Breast Cancer (2018)

Article

Injured astrocytes are repaired by Synaptotagmin XI-regulated lysosome exocytosis

Astrocytes are known to facilitate repair following brain injury; however, little is known about how injured astrocytes repair themselves. Repair of cell membrane injury requires Ca²⁺-triggered vesicle exocytosis...

S C Sreetama, T Takano, M Nedergaard, S M Simon… in Cell Death & Differentiation (2016)

Article

Early and mid-term results of transapical and right axillary artery cannulation for acute aortic dissection

T Terasaki, T Takano, T Fujii, K Komatsu, Y Ohtsu… in Journal of Cardiothoracic Surgery (2013)

Article

Aortic regurgitation and aortic valve replacement during repair of acute aortic dissection

T Yamamoto, T Takano, T Terasaki, Y Wada, T Seto… in Journal of Cardiothoracic Surgery (2013)

Article

Early results of aortic root reoperation

T Gomibuchi, T Takano, K Komatsu, Y Ohtsu, T Terasaki… in Journal of Cardiothoracic Surgery (2013)

Article

Cytokine and chemokine response in children with the 2009 pandemic influenza A (H1N1) virus infection

We report the systemic cytokine and chemokine response in children with the 2009 pandemic influenza A (H1N1) virus infection. In patients with pneumonia, the serum levels of IFN-γ and IL-5 were significantly h...

T. Takano, H. Tajiri, Y. Kashiwagi… in European Journal of Clinical Microbiology … (2011)

Article

BRAF^V600E mutation in anaplastic thyroid carcinomas and their accompanying differentiated carcinomas

Frequency of a BRAF^V600E mutation in anaplastic thyroid carcinoma, which is thought to be derived mainly from papillary carcinoma by multi-step carcinogenesis, is much lower than that in papillary carcinomas. To ...

T Takano, Y Ito, M Hirokawa, H Yoshida, A Miyauchi in British Journal of Cancer (2007)

Article

Clinical outcome and risk factors for recurrence in borderline ovarian tumours

We investigated the long-term prognosis of borderline ovarian tumours and determined risk factors for recurrence. One hundred and twenty-one borderline ovarian tumours treated between 1994 and 2003 at the part...

Y Yokoyama, T Moriya, T Takano, T Shoji, O Takahashi… in British Journal of Cancer (2006)

Article

High-throughput differential screening of mRNAs by serial analysis of gene expression: decreased expression of trefoil factor 3 mRNA in thyroid follicular carcinomas

To find mRNAs whose expression differs between thyroid follicular adenomas and carcinomas, a high-throughput analysis of mRNAs in these two tumours was performed. This method, named high-throughput differentia...

T Takano, A Miyauchi, H Yoshida, K Kuma, N Amino in British Journal of Cancer (2004)

Article

A novel apolipoprotein E5 variant with a 24-bp insertion causing hyperlipidemia

A tandem 24-bp insertion in the apolipoprotein E (apo E) gene was detected in a patient with elevated triglyceride, apolipoprotein (apo) CII, and apo CIII levels. This novel variant, apo E5ss, showed in position...

Y. Yamanouchi, T. Takano, H. Hamaguchi, K. Tokunaga in Journal of Human Genetics (2001)

Article

Quantitative measurement of thyroglobulin mRNA in peripheral blood of patients after total thyroidectomy

Previous studies have reported the clinical usefulness of reverse transcription-polymerase chain reaction (RT-PCR) detection of thyroglobulin (TG) mRNA in the peripheral blood of patients with differentiated t...

T Takano, A Miyauchi, H Yoshida, Y Hasegawa, K Kuma, N Amino in British Journal of Cancer (2001)

Article

Gene expression profiles in thyroid carcinomas

The gene expression profiles of human thyroid carcinomas were analysed by serial analysis of gene expression (SAGE) which allows quantitative and simultaneous analysis of a large number of transcripts. More th...

T Takano, Y Hasegawa, F Matsuzuka, A Miyauchi, H Yoshida… in British Journal of Cancer (2000)