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Open AccessHuman Brain Organoid Research and Applications: Where and How to Meet Legal Challenges?
An ethical and legal framework is needed to regulate the rapidly develo** human brain organoid research field properly. However, considering the legal issues involved in human brain organoid research remains...
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Article
Cross-dominant surgery using the da Vinci (**) surgical system in advanced rectal cancer surgery
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Article
Feasibility of laparoscopic-assisted transanal pelvic exenteration in locally advanced rectal cancer with anterior invasion
Transanal (Ta) pelvic exenteration is a promising, minimally invasive method for treating locally advanced colorectal cancer. However, since it is technically difficult to perform, Ta pelvic exenteration is ra...
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A novel technique of securing a clear surgical space using a silicone disc during transanal total mesorectal excision
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Article
The formation of intermetallic compounds in aluminium alloy to copper friction-welded joints and their effect on joint efficiency
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Friction welding of AZ31 magnesium alloy
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Gasless, video endoscopic transanal excision for carcinoid and laterally spreading tumors of the rectum
Background: The aim of this study is to determine whether gasless, video endoscopic transanal–rectal tumor excision (gasless VTEM) is a valid treatment for rectal carcinoid and laterally ...
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Article
Frequency of broncho-bronchiolar disease in rheumatoid arthritis: an examination by high-resolution computed tomography
To assess the frequency of pulmonary changes in patients with rheumatoid arthritis (RA), we evaluated a subject group (all outpatients with RA visiting the hospital during a period of three consecutive days) ...
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Article
Prenatal ultrasonographic appearance of type IIId (uncorrectable type with cystic dilatation) biliary atresia
Although prenatal ultrasonographic (US) diagnosis has been reported in biliary atresia (BA), most cases are type I (correctable with cystic dilatation). We report three prenatal cases of type IIId BA (uncorrec...
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Article
Development of large pseudocysts adjacent to the knee joint in rheumatoid arthritis. Assessment of radiological and histopathological approaches
This study examined the pathogenesis of large pseudocysts adjacent to knee joints in rheumatoid arthritis (RA). The radiological and histopathological features of 17 large subarticular pseudocysts in 12 knee ...
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Article
The effect of phospholipids and fatty acids on tight-junction permeability and bacterial translocation
The activity of phospholipase A2 (PLA2) is elevated in the intestinal epithelia of patients with inflammatory bowel disease (IBD). We recently reported that PLA2 mediates hydrolysis of phosphatidylcholine (PC) t...
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Article
Effect of secretory immunoglobulin A on bacterial translocation in an enterocyte-lymphocyte co-culture model
Intestinal secretory immunoglobulin A (sIgA) plays an important role in gut mucosal immunity in vivo; however, in-vitro enterocyte models for studying the mechanisms of these effects are lacking. This study u...
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Article
Extralobar pulmonary sequestration with venous drainage to the portal vein: a case report
Venous drainage to the portal vein in pulmonary sequestration is rare. A 7-month-old girl was referred to our hospital following surgery for ventricular septal defect because of a left upper abdominal mass wi...
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Article
The effect of phospholipase A2 on bacterial translocation in a cell culture model
The activity of phospholipase (PL)A2 is elevated in the intestinal epithelia of patients with inflammatory bowel disease (IBD). Recently, we reported that lysophosphatidylcholine (L-PC), the PLA2 hydrolysis prod...
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Article
Clinical significance of the lung/thorax transverse-area ratio in fetuses with cystic lung disease
We examined the clinical significance of the lung-thorax transverse-area ratio (L/T) in fetuses with cystic lung disease (CLD). The transverse section of the thorax was analyzed at the level of the 4-chamber ...
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Article
Open AccessCaspase-3 activation during apoptosis caused by glutathione–doxorubicin conjugate
Glutathione–doxorubicin (GSH–DXR) effectively induced apoptosis in rat hepatoma cells (AH66) at a lower concentration than DXR. After 24 h of drug treatment, DNA fragmentation of the cells was observed at the ...
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Article
Relationship between Ca-Dependent Change of Serum PTHand Extracellular Ca2+-Sensing Receptor Expression in Parathyroid Adenoma
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Physiologic stress responses to laparoscopic cholecystectomy
Background: Differences in the physiological stress response to pneumoperitoneal (PP) and gasless abdominal wall-lifting (AWL) procedures used for laparoscopic cholecystectomy have not been prope...
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Article
Prolonged preoperative stabilization using high-frequency oscillatory ventilation does not improve the outcome in neonates with congenital diaphragmatic hernia
Although delayed repair with preoperative stabilization using high-frequency oscillatory ventilation (HFOV) has been advocated in neonates with congenital diaphragmatic hernia (CDH), improved survival has not...
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Article
Three-color flow cytometry in the diagnosis of malignant lymphoma based on the comparative cell morphology of lymphoma cells and reactive lymphocytes
This study examines the identification of unusual cell populations highly associated with lymphoma cells (UCP-L) in diagnostic biopsy specimens using three-color flow cytometry (3-FCM). Patterns of surface ant...