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  1. Article

    Open Access

    Human Brain Organoid Research and Applications: Where and How to Meet Legal Challenges?

    An ethical and legal framework is needed to regulate the rapidly develo** human brain organoid research field properly. However, considering the legal issues involved in human brain organoid research remains...

    M. Kataoka, T.-L. Lee, T. Sawai in Journal of Bioethical Inquiry (2024)

  2. No Access

    Article

    Cross-dominant surgery using the da Vinci (**) surgical system in advanced rectal cancer surgery

    T. Nonaka, T. Tominaga, Y. Akazawa, T. Sawai, T. Nagayasu in Techniques in Coloproctology (2022)

  3. No Access

    Article

    Feasibility of laparoscopic-assisted transanal pelvic exenteration in locally advanced rectal cancer with anterior invasion

    Transanal (Ta) pelvic exenteration is a promising, minimally invasive method for treating locally advanced colorectal cancer. However, since it is technically difficult to perform, Ta pelvic exenteration is ra...

    T. Nonaka, T. Tominaga, Y. Akazawa, T. Sawai in Techniques in Coloproctology (2021)

  4. No Access

    Article

    A novel technique of securing a clear surgical space using a silicone disc during transanal total mesorectal excision

    T. Nonaka, T. Tominaga, Y. Akazawa, T. Sawai, T. Nagayasu in Techniques in Coloproctology (2020)

  5. No Access

    Article

    The formation of intermetallic compounds in aluminium alloy to copper friction-welded joints and their effect on joint efficiency

    H Ochi, K Ogawa, Y Yamamoto, G Kawai, T Sawai in Welding International (2004)

  6. No Access

    Article

    Friction welding of AZ31 magnesium alloy

    K Ogawa, H Yamaguchi, H Ochi, T Sawai, Y Suga, Y Oki in Welding International (2003)

  7. No Access

    Article

    Gasless, video endoscopic transanal excision for carcinoid and laterally spreading tumors of the rectum

    Background: The aim of this study is to determine whether gasless, video endoscopic transanal–rectal tumor excision (gasless VTEM) is a valid treatment for rectal carcinoid and laterally ...

    T. Nakagoe, H. Ishikawa, T. Sawai, T. Tsuji in Surgical Endoscopy And Other Interventiona… (2003)

  8. No Access

    Article

    Frequency of broncho-bronchiolar disease in rheumatoid arthritis: an examination by high-resolution computed tomography

     To assess the frequency of pulmonary changes in patients with rheumatoid arthritis (RA), we evaluated a subject group (all outpatients with RA visiting the hospital during a period of three consecutive days) ...

    T. Izumiyama, H. Hama, M. Miura, A. Hatakeyama, Y. Suzuki, T. Sawai in Modern Rheumatology (2002)

  9. No Access

    Article

    Prenatal ultrasonographic appearance of type IIId (uncorrectable type with cystic dilatation) biliary atresia

    Although prenatal ultrasonographic (US) diagnosis has been reported in biliary atresia (BA), most cases are type I (correctable with cystic dilatation). We report three prenatal cases of type IIId BA (uncorrec...

    T. Hasegawa, T. Sasaki, T. Kimura, T. Sawai, K. Nose in Pediatric Surgery International (2002)

  10. No Access

    Article

    Development of large pseudocysts adjacent to the knee joint in rheumatoid arthritis. Assessment of radiological and histopathological approaches

     This study examined the pathogenesis of large pseudocysts adjacent to knee joints in rheumatoid arthritis (RA). The radiological and histopathological features of 17 large subarticular pseudocysts in 12 knee ...

    M. Yoshida, S. Ichinohe, M. Uzuki, W. Yoshida, T. Sawai in Modern Rheumatology (2002)

  11. No Access

    Article

    The effect of phospholipids and fatty acids on tight-junction permeability and bacterial translocation

     The activity of phospholipase A2 (PLA2) is elevated in the intestinal epithelia of patients with inflammatory bowel disease (IBD). We recently reported that PLA2 mediates hydrolysis of phosphatidylcholine (PC) t...

    T. Sawai, R. A. Drongowski, R. W. Lampman, A. G. Coran in Pediatric Surgery International (2001)

  12. No Access

    Article

    Effect of secretory immunoglobulin A on bacterial translocation in an enterocyte-lymphocyte co-culture model

     Intestinal secretory immunoglobulin A (sIgA) plays an important role in gut mucosal immunity in vivo; however, in-vitro enterocyte models for studying the mechanisms of these effects are lacking. This study u...

    T. Sawai, N. Goldstone, R. A. Drongowski, A. G. Coran in Pediatric Surgery International (2001)

  13. No Access

    Article

    Extralobar pulmonary sequestration with venous drainage to the portal vein: a case report

    Venous drainage to the portal vein in pulmonary sequestration is rare. A 7-month-old girl was referred to our hospital following surgery for ventricular septal defect because of a left upper abdominal mass wi...

    S. Kamata, T. Sawai, K. Nose, T. Hasagawa, K. Nakajima, H. Soh in Pediatric Radiology (2000)

  14. No Access

    Article

    The effect of phospholipase A2 on bacterial translocation in a cell culture model

     The activity of phospholipase (PL)A2 is elevated in the intestinal epithelia of patients with inflammatory bowel disease (IBD). Recently, we reported that lysophosphatidylcholine (L-PC), the PLA2 hydrolysis prod...

    T. Sawai, N. Usui, J. Dwaihy, R. A. Drongowski, A. Abe in Pediatric Surgery International (2000)

  15. No Access

    Article

    Clinical significance of the lung/thorax transverse-area ratio in fetuses with cystic lung disease

    We examined the clinical significance of the lung-thorax transverse-area ratio (L/T) in fetuses with cystic lung disease (CLD). The transverse section of the thorax was analyzed at the level of the 4-chamber ...

    S. Kamata, S. Ishikawa, N. Usui, T. Sawai, Y. Kitayama in Pediatric Surgery International (1999)

  16. Article

    Open Access

    Caspase-3 activation during apoptosis caused by glutathione–doxorubicin conjugate

    Glutathione–doxorubicin (GSH–DXR) effectively induced apoptosis in rat hepatoma cells (AH66) at a lower concentration than DXR. After 24 h of drug treatment, DNA fragmentation of the cells was observed at the ...

    T Asakura, T Sawai, Y Hashidume, Y Ohkawa, S Yokoyama in British Journal of Cancer (1999)

  17. No Access

    Article

    Relationship between Ca-Dependent Change of Serum PTHand Extracellular Ca2+-Sensing Receptor Expression in Parathyroid Adenoma

    C. Kaneko, K. Mizunashi, M. Tanaka, M. Uzuki, M. Kikuchi in Calcified Tissue International (1999)

  18. No Access

    Article

    Physiologic stress responses to laparoscopic cholecystectomy

    Background: Differences in the physiological stress response to pneumoperitoneal (PP) and gasless abdominal wall-lifting (AWL) procedures used for laparoscopic cholecystectomy have not been prope...

    A. Nanashima, H. Yamaguchi, T. Tsuji, E. Yamaguchi, T. Sawai in Surgical Endoscopy (1998)

  19. Article

    Prolonged preoperative stabilization using high-frequency oscillatory ventilation does not improve the outcome in neonates with congenital diaphragmatic hernia

    Although delayed repair with preoperative stabilization using high-frequency oscillatory ventilation (HFOV) has been advocated in neonates with congenital diaphragmatic hernia (CDH), improved survival has not...

    S. Kamata, N. Usui, S. Ishikawa, H. Okuyama, Y. Kitayama in Pediatric Surgery International (1998)

  20. No Access

    Article

    Three-color flow cytometry in the diagnosis of malignant lymphoma based on the comparative cell morphology of lymphoma cells and reactive lymphocytes

    This study examines the identification of unusual cell populations highly associated with lymphoma cells (UCP-L) in diagnostic biopsy specimens using three-color flow cytometry (3-FCM). Patterns of surface ant...

    R Ichinohasama, JF DeCoteau, J Myers, ME Kadin, T Sawai, K Ooya in Leukemia (1997)

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