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  1. Article

    Open Access

    Rationale and design of the iCORONARY trial: improving the cost-effectiveness of coronary artery disease diagnosis

    In patients with stable coronary artery disease (CAD), revascularisation decisions are based mainly on the visual grading of the severity of coronary stenosis on invasive coronary angiography (ICA). However, i...

    J. Peper, L. M. Becker, T. A. Bruning, R. P. J. Budde in Netherlands Heart Journal (2023)

  2. Article

    Open Access

    Systematic assessment of coronary calcium detectability and quantification on four generations of CT reconstruction techniques: a patient and phantom study

    In computed tomography, coronary artery calcium (CAC) scores are influenced by image reconstruction. The effect of a newly introduced deep learning-based reconstruction (DLR) on CAC scoring in relation to othe...

    M. M. Dobrolinska, G. D. van Praagh in The International Journal of Cardiovascula… (2023)

  3. Article

    Open Access

    Right atrial and ventricular strain detects subclinical changes in right ventricular function in precapillary pulmonary hypertension

    Right ventricular (RV) ejection fraction (EF) by cardiac magnetic resonance (CMR) correlates to outcome in precapillary pulmonary hypertension (pPH) patients, but is insensitive to early changes. Strain might ...

    J. L. Vos, T. Leiner, A. P. J. van Dijk in The International Journal of Cardiovascula… (2022)

  4. No Access

    Article

    Improved coronary calcium detection and quantification with low-dose full field-of-view photon-counting CT: a phantom study

    The aim of the current study was to systematically assess coronary artery calcium (CAC) detection and quantification for spectral photon-counting CT (SPCCT) in comparison to conventional CT and, in addition, t...

    N. R. van der Werf, P. A. Rodesch, S. Si-Mohamed in European Radiology (2022)

  5. Article

    Open Access

    Coronary calcium scoring potential of large field-of-view spectral photon-counting CT: a phantom study

    The aim of the current study was, first, to assess the coronary artery calcium (CAC) scoring potential of spectral photon-counting CT (SPCCT) in comparison with computed tomography (CT) for routine clinical pr...

    Niels R. van der Werf, S. Si-Mohamed, P. A. Rodesch in European Radiology (2022)

  6. Article

    Open Access

    The impact and challenges of implementing CTCA according to the 2019 ESC guidelines on chronic coronary syndromes: a survey and projection of CTCA services in the Netherlands

    The 2019 ESC-guidelines on chronic coronary syndromes (ESC-CCS) recommend computed tomographic coronary angiography (CTCA) or non-invasive functional imaging instead of exercise ECG as initial test to diagnose...

    T. P. W. van den Boogert, B. E. P. M. Claessen, S. M. Boekholdt in Insights into Imaging (2021)

  7. Article

    Open Access

    Correction to: Evaluation of non-invasive imaging parameters in coronary microvascular disease: a systematic review

    F. Groepenhof, R. G. M. Klaassen, G. B. Valstar, S. H. Bots in BMC Medical Imaging (2021)

  8. Article

    Open Access

    Added value of computed tomography fractional flow reserve in the diagnosis of coronary artery disease

    Multiple non-invasive tests are performed to diagnose coronary artery disease (CAD), but all are limited to either anatomical or functional assessments. Computed tomography derived Fractional Flow Reserve (CT-...

    J. Peper, J. Schaap, J. C. Kelder, B. J. W. M. Rensing, D. E. Grobbee in Scientific Reports (2021)

  9. Article

    Open Access

    Evaluation of non-invasive imaging parameters in coronary microvascular disease: a systematic review

    Coronary microvascular dysfunction (CMD) is an important underlying cause of angina pectoris. Currently, no diagnostic tool is available to directly visualize the coronary microvasculature. Invasive microvascu...

    F. Groepenhoff, R. G. M. Klaassen, G. B. Valstar, S. H. Bots in BMC Medical Imaging (2021)

  10. Article

    Open Access

    Randomised comparison of a balloon-expandable and self-expandable valve with quantitative assessment of aortic regurgitation using magnetic resonance imaging

    Transcatheter aortic valve implantation (TAVI) is a safe and effective treatment for inoperable, intermediate- or high-risk patients with severe symptomatic aortic stenosis and has been associated with excelle...

    N. H. M. Kooistra, M. Abawi, M. Voskuil, K. Urgel, M. Samim in Netherlands Heart Journal (2020)

  11. Article

    Open Access

    Eliminating biasing signals in lung cancer images for prognosis predictions with deep learning

    Deep learning has shown remarkable results for image analysis and is expected to aid individual treatment decisions in health care. Treatment recommendations are predictions with an inherently causal interpret...

    W. A. C. van Amsterdam, J. J. C. Verhoeff, P. A. de Jong, T. Leiner in npj Digital Medicine (2019)

  12. Article

    Open Access

    Artificial intelligence for the general cardiologist

    J. Verjans, T. Leiner in Netherlands Heart Journal (2019)

  13. Article

    Open Access

    Enhancing cardiovascular artificial intelligence (AI) research in the Netherlands: CVON-AI consortium

    Machine learning (ML) allows the exploration and progressive improvement of very complex high-dimensional data patterns that can be utilised to optimise specific classification and prediction tasks, outperform...

    J. W. Benjamins, K. van Leeuwen, L. Hofstra, M. Rienstra in Netherlands Heart Journal (2019)

  14. Article

    Open Access

    Artificial intelligence in cardiovascular imaging: state of the art and implications for the imaging cardiologist

    Healthcare, conceivably more than any other area of human endeavour, has the greatest potential to be affected by artificial intelligence (AI). This potential has been shown by several reports that demonstrate...

    K. R. Siegersma, T. Leiner, D. P. Chew, Y. Appelman in Netherlands Heart Journal (2019)

  15. Article

    Open Access

    Validation of aortic valve 4D flow analysis and myocardial deformation by cardiovascular magnetic resonance in patients after the arterial switch operation

    Aortic regurgitation (AR) and subclinical left ventricular (LV) dysfunction expressed by myocardial deformation imaging are common in patients with transposition of the great arteries after the arterial switch...

    W. H. S. van Wijk, J. M. P. J. Breur in Journal of Cardiovascular Magnetic Resonan… (2019)

  16. Article

    Open Access

    Cardio-oncology: an overview on outpatient management and future developments

    Recent advances in the early detection and treatment of cancer have led to increasing numbers of cancer survivors worldwide. Nonetheless, despite major improvements in the outcome of these patients, long-term ...

    A. J. Teske, M. Linschoten, J. A. M. Kamphuis in Netherlands Heart Journal (2018)

  17. Article

    Open Access

    Influence of heart rate on coronary calcium scores: a multi-manufacturer phantom study

    To evaluate the influence of heart rate on coronary calcium scores (CCS) using a dynamic phantom on four high-end computed tomography (CT) systems from different manufacturers. Artificial coronary arteries wer...

    N. R. van der Werf, M. J. Willemink in The International Journal of Cardiovascula… (2018)

  18. Article

    Open Access

    Influence of iterative reconstruction on coronary calcium scores at multiple heart rates: a multivendor phantom study on state-of-the-art CT systems

    The objective of this study was to evaluate the influence of iterative reconstruction on coronary calcium scores (CCS) at different heart rates for four state-of-the-art CT systems. Within an anthropomorphic c...

    N. R. van der Werf, M. J. Willemink in The International Journal of Cardiovascula… (2018)

  19. Article

    Open Access

    The Effects of Iodine Attenuation on Pulmonary Nodule Volumetry using Novel Dual-Layer Computed Tomography Reconstructions

    To assess the effect of iodine attenuation on pulmonary nodule volumetry using virtual non-contrast (VNC) and mono-energetic reconstructions.

    A. M. den Harder, F. Bangert, R. W. van Hamersvelt, T. Leiner in European Radiology (2017)

  20. Article

    Open Access

    Influence of dose reduction and iterative reconstruction on CT calcium scores: a multi-manufacturer dynamic phantom study

    To evaluate the influence of dose reduction in combination with iterative reconstruction (IR) on coronary calcium scores (CCS) in a dynamic phantom on state-of-the-art CT systems from different manufacturers. ...

    N. R. van der Werf, M. J. Willemink in The International Journal of Cardiovascula… (2017)

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