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Article
Open AccessPersonalized bacteriophage therapy to treat pandrug-resistant spinal Pseudomonas aeruginosa infection
Bone and joint infections (BJI) are one of the most difficult-to-treat bacterial infection, especially in the era of antimicrobial resistance. Lytic bacteriophages (phages for short) are natural viruses that c...
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Article
Should we expand the indications for the DAIR (debridement, antibiotic therapy, and implant retention) procedure for Staphylococcus aureus prosthetic joint infections? A multicenter retrospective study
To evaluate factors associated with failure in patients treated with DAIR (debridement, antibiotic therapy, and implant retention) for Staphylococcus aureus prosthetic joint infections (PJIs). We retrospectively ...
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Article
Prolonged suppressive antibiotic therapy for prosthetic joint infection in the elderly: a national multicentre cohort study
During prosthetic joint infection (PJI), optimal surgical management with exchange of the device is sometimes impossible, especially in the elderly population. Thus, prolonged suppressive antibiotic therapy (P...
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Article
High burden of BK virus-associated hemorrhagic cystitis in patients undergoing allogeneic hematopoietic stem cell transplantation
BK virus (BKV) reactivation has been increasingly associated with the occurrence of late-onset hemorrhagic cystitis (HC) after allogeneic hematopoietic SCT (allo-HSCT) resulting in morbidity and sometimes mort...
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Article
The challenge of infection prevention in spine surgery: an update
Prevention is particularly challenging in implant-associated bone and joint infection, as it could reduce the following: (1) the risk of infection in particular patient populations; (2) the risk associated wit...
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Article
The follow-up of patients with postoperative infection of the spine
The follow-up of patients with postoperative infection of the spine required a multidisciplinary teamwork under the guidance of the spine surgeon and the infectious disease (ID) specialist. During follow-up, t...
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Article
Prevalence of isolates with reduced glycopeptide susceptibility in orthopedic device-related infections due to methicillin-resistant Staphylococcus aureus
We evaluated, by an improved susceptibility testing method, the prevalence and significance of low-level glycopeptide resistance in methicillin-resistant Staphylococcus aureus (MRSA) isolates, which belonged to a...
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Article
Chocs toxiques dans les infections à cocci à Gram positif
Bien que les cocci à Gram positifs soient impliqués dans la moitié des causes de sepsis documentés, les chocs toxiques liés à ces bactéries sont rares. Par définition, le choc toxique, qu’il soit d’origine sta...
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Article
Open AccessSwitch to once or twice daily unboosted atazanavir in a cohort of stable HIV patients: strong differences in drug exposure and virological outcome
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Article
Risk factors for treatment failure in orthopedic device-related methicillin-resistant Staphylococcus aureus infection
The purpose of this study was to determine the clinical and microbiological risk factors for treatment failure of methicillin-resistant Staphylococcus aureus (MRSA) orthopedic device-related infection (ODRI). A r...
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Article
In vivo and in vitro detection of a superantigenic toxin Vbeta signature in two forms of streptococcal toxic shock syndrome
The aim of this study was to examine the production of superantigenic toxins in vivo and in vitro in two patients with streptococcal toxic shock syndrome (TSS). In the first patient, a woman with puerperal fev...
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Article
One in five mortality in non-menstrual toxic shock syndrome versus no mortality in menstrual cases in a balanced French series of 55 cases
Staphylococcus aureus superantigenic toxins are responsible for menstrual and non-menstrual toxic shock syndrome (TSS). We compared the clinical and biological characteristics of 21 cases of menstrual TSS (MTSS) ...
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Article
Possibly Linezolid-Induced Peripheral and Central Neurotoxicity: Report of Four Cases
Linezolid is the first member of the new synthetic class of antibacterial agents that prevent the formation of the 70S ribosomal subunit. It represents an attractive choice in the therapeutic arsenal because i...
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Article
Severe peritonitis due to Balantidium coli acquired in France
The case reported here concerns an alcoholic pork-butcher who presented with severe colitis with peritonitis, caused by the only ciliate protozoan capable of infecting humans, Balantidium coli. This parasite is c...
