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  1. No Access

    Article

    Alpha-1-microglobulin: inhibitory effect on calcium oxalate crystallization in vitro and decreased urinary concentration in calcium oxalate stone formers

    In the past few years, alpha-1-microglobulin (α1m) has been copurified from human urine with bikunin, a potent inhibitor of calcium oxalate (CaOx) crystallization in vitro. In this study, we have purified α1m...

    S. Tardivel, J. Médétognon, C. Randoux, M. Kébédé, T. Drüeke… in Urological Research (1999)

  2. No Access

    Article

    Inhibitory effect of bikunin on calcium oxalate crystallization in vitro and urinary bikunin decrease in renal stone formers

    Two proteins of 17 and 24 kDa, respectively, which were immunologically related to bikunin, were purified from urine of healthy men, using in the last step a trypsin CNBr-sepharose affinity column. These prot...

    J. Médétognon-Benissan, S. Tardivel, C. Hennequin, M. Daudon… in Urological Research (1999)

  3. No Access

    Article

    Reduced inhibitory activity of uronic-acid-rich protein in urine of stone formers

    We recently reported that human urine contains a newly identified urinary glycoprotein acting as a potent inhibitor against calcium oxalate crystallization. This inhibitor is a uronic-acid-rich protein (UAP) w...

    F. Atmani, B. Lacour, P. Jungers, T. Drüeke, M. Daudon in Urological Research (1994)

  4. No Access

    Chapter

    Parathyroid Hormone and Lipid Metabolism

    In addition to its well known actions on classic target organs, it has become apparent in recent years that parathyroid hormone (PTH) exerts effects in many other tissues. Thus, PTH has also well-defined effec...

    T. Drüeke, J.-B. Roullet, B. Lacour in New Actions of Parathyroid Hormone (1989)

  5. No Access

    Article

    Multiorgan aluminium deposits in a chronic haemodialysis patient

    The study reports an aluminium-intoxicated haemodialysis patient who had encephalopathy, osteomalacia and congestive cardiomyopathy prior to his death. Detailed light and electron microscope examination reveal...

    A. Roth, C. Nogues, P. Galle, T. Drüeke in Virchows Archiv A (1984)

  6. No Access

    Chapter and Conference Paper

    Hormone Regulation of Intestinal Calcium and Phosphate Transport: Effects of Vitamin D, Parathyroid Hormone (PTH) and Calcitonin (CT)

    Calcium (Ca) and phosphate (Pi) movement across the intestinal wall involves an active or facilitated, saturable, as well as a passive, non-saturable transport component. The transport proceeds almost certainly v...

    T. Drüeke, B. Lacour in Intestinal Transport (1983)

  7. No Access

    Chapter and Conference Paper

    Symposium Pathomechanismen der chronischen Niereninsuffizienz und Hämodialyse

    Für die Anämie des progredienten Nierenversagens ist neben den bekannten Faktoren wie Mikroblutungen, Hämolyse und Erythropoetinmangel auch eine Störung der Regeneration der Erythrozyten verantwortlich. Sie wird ...

    H. W. Radtke, H. J. Kramer, D. Klingmüller… in Verhandlungen der Deutschen Gesellschaft f… (1983)

  8. No Access

    Chapter

    Effect of Parathyroid Hormone on Rat Enterocyte Na Transport in Vitro

    Parathyroid Hormone (PTH) influences renal (1,2) and intestinal (3,4) handling of Na and water. In the intestine, it is not clearly established whether the observed effects are due to a direct action of the ho...

    T. Drüeke, B. Lacour, E. Pierandrei… in Regulation of Phosphate and Mineral Metabo… (1982)

  9. No Access

    Article

    Binding of tienilic acid (Diflurex®) to human serum albumin and to plasma of normal subjects and uraemic patients

    The binding of tienilic acid (TA) 2,3-dichloro-4-(2-thienyl-carbonyl) phenoxyacetic acid, a new diuretic, to human serum albumin (HSA) and to the plasma of 12 uraemic patients under treatment with haemodialysi...

    J. Prandota, J. P. Tillement, Ph. d’Athis… in European Journal of Drug Metabolism and Ph… (1980)

  10. No Access

    Chapter

    Effect of Acute Ethanol Loading on Parathyroid Gland Secretion in the Rat

    Ethanol as well as other anesthetic agents such as methanol, chloral hydrate and urethane can induce hypocalcemia in the rat when ingested at anesthetic dosage (5).

    J. Chanard, B. Lacour, T. Drüeke… in Phosphate and Minerals in Health and Disea… (1980)

  11. No Access

    Chapter

    Role of Phosphate in the Resistance to Intestinal Effects of Parathyroid Hormone in Rats with Chronic Renal Failure

    PTH decreases phosphate reabsorption in the proximal renal tubule and also at more distal tubular sites (1). In contrast to this in vivo effect, PTH has been reported to increase cellular uptake of 32P04 in vitro...

    T. Drüeke, B. Lacour, J. Chanard in Phosphate and Minerals in Health and Disease (1980)

  12. No Access

    Chapter

    Effect of Parathyroid Hormone and Volume Expansion on Jejunal Calcium, Sodium, and Water Transport in the Rat

    It seems well established that parathyroid hormone (PTH) increases intestinal calcium absorption and that this effect is indirect, possibly via enhanced production of 1,25 dihydroxy-cholecalciferol (1, 25-(OH)2 D

    T. Drüeke, J. Chanard, E. Pujade-Lauraine, B. Lacour… in Phosphate Metabolism (1977)

  13. No Access

    Article

    Effect of sodium deoxycholate on net transintestinal movement in the uraemic rat: Acute experiments

    In vivo gelingt der Nachweis, dass der Transport von Kreatinin, Phosphor, Natrium und Kalium vom Blut in das Lumen des Dünndarms bei urämischen Ratten durch Natriumdesoxycholat gesteigert wird.

    T. Drüeke, D. Ganeval, Cl. Marche in Experientia (1972)