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  1. Article

    Open Access

    Metformin inhibits melanoma development through autophagy and apoptosis mechanisms

    Metformin is the most widely used antidiabetic drug because of its proven efficacy and limited secondary effects. Interestingly, recent studies have reported that metformin can block the growth of different tu...

    T Tomic, T Botton, M Cerezo, G Robert, F Luciano, A Puissant… in Cell Death & Disease (2011)

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  2. Article

    Ciglitazone negatively regulates CXCL1 signaling through MITF to suppress melanoma growth

    We have previously demonstrated that the thiazolidinedione ciglitazone inhibited, independently of PPARγ activation, melanoma cell growth. Further investigations now show that ciglitazone effects are mediated thr...

    T Botton, A Puissant, Y Cheli, T Tomic, S Giuliano, L Fajas… in Cell Death & Differentiation (2011)

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