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Article
Evaluation of potential mechanisms underlying genotype–phenotype correlations in multiple endocrine neoplasia type 2
Distinct dominant activating mutations in the RET proto-oncogene are responsible for the development of multiple endocrine neoplasia type 2 (MEN 2). Concise examination of the mutated codons led to the detection ...
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Article
Adenovirus-mediated TA-p73β gene transfer increases chemosensitivity of human malignant melanomas
Malignant melanoma is the most aggressive form of skin cancer and has proven to be highly resistant to conventional chemotherapy. Intriguingly, the p53 tumor suppressor, a main mediator of chemoresistance in o...