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Gonadotropin levels in urine during early postnatal period in small for gestational age preterm male infants with fetal growth restriction
The objective of this study was to estimate gonadotropin concentrations in small for gestational age (SGA) male infants with the reactivation of the hypothalamic–pituitary–gonadal axis during the first few mon...
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Article
Oxygen ultra-fine bubbles water administration prevents bone loss of glucocorticoid-induced osteoporosis in mice by suppressing osteoclast differentiation
Oxygen ultra-fine bubbles (OUB) saline injection prevents bone loss of glucocorti\coid-induced osteoporosis in mice, and OUB inhibit osteoclastogenesis via RANK-TRAF6-c-Fos-NFATc1 signaling and RANK-p38 MAPK s...
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Open AccessESICM LIVES 2016: part three
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Open AccessESICM LIVES 2016: part two
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Post-transplantation-emerging anti-HLA DQA1/DQB1 antibody possibly responsible for graft rejection after myeloablative-unrelated marrow grafting
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Open AccessEvaluation of complications of administration for tolvaptan after fluid resuscitation in critical care
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Epidemiology of operation-related medical errors in inpatients in Japan: the JET study
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A phase II study of metronomic paclitaxel/cyclophosphamide/capecitabine followed by 5-fluorouracil/epirubicin/cyclophosphamide as preoperative chemotherapy for triple-negative or low hormone receptor expressing/HER2-negative primary breast cancer
Better treatments for triple-negative breast cancer (TNBC) are needed. To address this need, we studied the effects of preoperative metronomic paclitaxel/cyclophosphamide/capecitabine (mPCX) followed by 5-fluo...
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Article
Feasibility of marrow harvesting from pediatric sibling donors without hematopoietic growth factors and allotransfusion
We retrospectively studied 108 marrow harvests from 105 pediatric sibling donors. The median age of donors was 8 years (range: 1–15) and the median body weight was 27 kg (range: 10–100). The volumes of aspirat...
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Open AccessRandomized trial of preoperative docetaxel with or without capecitabine after 4 cycles of 5-fluorouracil–epirubicin–cyclophosphamide (FEC) in early-stage breast cancer: exploratory analyses identify Ki67 as a predictive biomarker for response to neoadjuvant chemotherapy
This randomized, multicenter study compared the efficacy of docetaxel with or without capecitabine following fluorouracil/epirubicin/cyclophosphamide (FEC) therapy in operable breast cancer and investigated t...
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Open AccessInfluence of adverse drug events on the mortality and the length of hospital stay in ICUs in Japan: the JADE Study
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Alternative donor marrow transplantation in children with aplastic anemia using low-dose irradiation and fludarabine-based conditioning
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Therapy-related myelodysplastic syndrome of recipient origin in a juvenile myelomonocytic leukemia patient 17 years after allogeneic BMT
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High incidence of fatty liver and insulin resistance in long-term adult survivors of childhood SCT
Overweight/obesity among adult survivors of childhood SCT has been considered to be predictive of eventual development of metabolic abnormalities. Fatty liver is increasingly recognized as a major cause of liv...
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Extrinsic compression Bow hunter’s stroke
Bow hunter’s stroke is a symptomatic vertebrobasilar insufficiency caused by stenosis or occlusion of the vertebral artery at the C1–C2 level with head rotation. This definition excludes symptoms related to ex...
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Gonadal shielding to irradiation is effective in protecting testicular growth and function in long-term survivors of bone marrow transplantation during childhood or adolescence
An increasing number of long-term surviving bone marrow transplantation (BMT) recipients have recovered from their primary disease but are at risk of develo** failure of endocrine organs. We investigated 30 ...
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Negative correlation between bone mineral density and TSH receptor antibodies in male patients with untreated Graves’ disease
Although it has been established that hyperthyroidism leads to reduced bone mineral density (BMD), with accelerated bone turnover promoting bone resorption in female patients, there is a dearth of data for mal...
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Article
Association between patient education and health-related quality of life in patients with Parkinson's disease
Background: Providing patients with disease- and treatment-related information is an important role of medical staff and is now reimbursed in Japan by the national health insurance system under the rubric ‘patie...
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Apoptosis and Cell Proliferation of Small Intestinal Villi in Mitomycin C-Treated Rats
Mitomycin C (MMC) therapy often causes toxicity affecting the small intestine. We investigated the relationship between pathological manifestations and cell death, or the proliferation of small intestinal vill...
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Primary Breast Cancer Patients Treated with Breast-Conserving Therapy and Tamoxifen
To study whether Japanese breast cancer patients obtain favourable results with breast-conserving surgery if the same selection criteria as those for Western patients are used, and, simultaneously, to assess t...