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    Article

    Adsorption and pharmacokinetics of cyclosporin A in relation to mode of infusion in bone marrow transplant patients

    Two main factors that affect the pharmacokinetics of cyclosporin A (CsA) during 24-h durable intravenous (DIV) administration have been reported, namely physiological changes after bone marrow transplantation,...

    N Shibata, Y Ikuno, Y Tsubakimoto, N Hoshino, T Minouchi in Bone Marrow Transplantation (2000)

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    Article

    Preferential inhibition of CYP1A enzymes in hepatic microsomes by mexiletine

    We examined the inhibitory behavior of theophylline oxidations and a variety of cytochrome P450 (P450)-dependent metabolism in the presence of mexiletine (MEX), using hepatic microsomes from both control mice ...

    H. Konishi, K. Morita, T. Minouchi in European Journal of Drug Metabolism and Ph… (1999)

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    Article

    Relationship between erythrocyte-to-plasma distribution ratio of cyclosporin and lymphocyte proliferation in renal transplant patients

    Objective: The aim of this study was to examine the relationship between erythrocyte-to-plasma distribution ratio of cyclosporin (CsA-EP) and lymphocyte proliferation as an indicator of ...

    N. Shibata, N. Hoshino, T. Minouchi, A. Yamaji in European Journal of Clinical Pharmacology (1997)

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    Article

    Blood-to-plasma distribution of cyclosporin A in a renal transplant recipient

    N. Shibata, T. Minouchi, Y. Hayashi in European Journal of Clinical Pharmacology (1988)