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Article
Open AccessGust alleviation by spanwise load control applied on a forward and backward swept wing
The present paper investigates the feasibility of gust load alleviation at transonic speeds on a backward swept and a forward swept transport aircraft configuration. Spanwise-distributed control surfaces at th...
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Reference Work Entry In depth
Aeroelastic Simulations Based on High-Fidelity CFD and CSD Models
This chapter focuses on the challenges rising when modeling the aeroelasticity of modern wind turbines utilizing high-fidelity methods. A comprehensive review of the state of the art is presented at the beginn...
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Article
Definition von Qualität in der Handchirurgie
Die Qualität der Behandlung unterliegt im Gesamtkontext des Gesundheitswesens multifaktoriellen Einflüssen. In dem Bestreben die Qualität der handchirurgischen Versorgung zu verbessern, haben die in der Deutsc...
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Living Reference Work Entry In depth
Aeroelastic Simulations Based on High-Fidelity CFD and CSD Models
This chapter focuses on the challenges rising when modeling the aeroelasticity of modern wind turbines utilizing high-fidelity methods. A comprehensive review of the state of the art is presented at the beginn...
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Article
Vom Symptom zur Diagnose – Tauglichkeit von Symptom-Checkern
Jede 7. Diagnose ist falsch. Jedes Jahr könnten 1,5 Mio. Menschen weltweit mit der richtigen Diagnose gerettet werden. Ärzte müssen mehr als 20.000 Ursachen berücksichtigen. Wissenschaftler der Harvard-Univers...
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Article
Development of flow structures in the near-field wake region of the Common Research Model
The flow in the near-field wake region of a generic transport aircraft configuration has been studied using both unsteady RANS and delayed detached-eddy simulations. The NASA Common Research Model has been use...
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Article
Open AccessIL-6 blockade in systemic juvenile idiopathic arthritis – achievement of inactive disease and remission (data from the German AID-registry)
Systemic juvenile idiopathic arthritis (sJIA) is a complex disease with an autoinflammatory component of unknown etiology related to the innate immune system. A major role in the pathogenesis has been ascribed...
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Chapter and Conference Paper
Numerical Study of Three-Dimensional Shock Control Bump Flank Effects on Buffet Behavior
Originally developed as a flow control device Shock Control Bumps (SCB) reduce wave drag of an aircraft wing at off-design in transonic speed effectively. Recently, another field of application for such bumps ...
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Article
Open AccessInterleukin (IL)- 6 inhibition - Follow-up data of the German AID-registry1
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Chapter and Conference Paper
Impact of 3D Shock Control Bumps on Transonic Buffet
Steady and unsteady RANS computations have been carried out to investigate the effect of three dimensional shock control bumps on the buffet behaviour of a transonic airfoil. A total of five basic bump shapes ...
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Chapter and Conference Paper
Numerical and Experimental Examination of Shock Control Bump Flow Physics
A method allowing a detailed investigation of the flow physics of shock control bumps (SCBs) on an unswept airfoil has been developed by comparison of the results of experiments and computations. A simple wind...
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Article
The rainbow cohort: 96 week follow-up of saquinavir-containing regimens in previously antiretroviral therapy (ART)-naïve and pre-treated but protease inhibitor (PI)- naïve hiv-infected patients
We have previously reported data from the German cohort of the multinational observational prospective RAINBOW survey which assessed the tolerability and efficacy of ritonavir-boosted saquinavir (SQV/r)-contai...
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Article
Uveitistherapie im Kindesalter
Die Uveitis im Kindesalter unterscheidet sich von Uveitismanifestationen im Erwachsenenalter nicht nur durch die Art und Schwere der Entzündung, sondern auch durch die häufig schlechtere Prognose sowie alterss...
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Article
Open AccessEfficacy and safety of TDF/FTC-containing, first-line HAART in clinical practice: 3-year data from the German outpatient cohort
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Article
Open Access0314. Efficacy and safety of peginterferon alfa-2a + RBV in cHCV/HIV- vs cHCV-infected patients: interim analysis of a multicenter German cohort
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Article
Schwangerschaftsassoziierte Osteoporose
Muskuloskelettale Schmerzen in der Schwangerschaft und Stillzeit stellen ein häufiges Symptom dar. Die Differentialdiagnosen reichen dabei von „normaler“ Begleiterscheinung über Knochenstoffwechselstörungen bi...
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Article
Safety and efficacy after switch to a saquinavir-containing antiretroviral regimen in protease inhibitor pretreated HIV-positive patients
The RAINBOW survey is a multinational observational study assessing the tolerability and efficacy of ritonavir-boosted saquinavir (SQV/r), using the 500 mg film-coated SQV formulation, in routine clinical prac...
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Article
Safety and Efficacy of a Saquinavir-Containing Antiretroviral Regimen in Previously ART-Naïve or Pretreated but Protease Inhibitor-Naïve HIV-Positive Patients
The RAINBOW survey is a multinational observational study assessing the tolerability and efficacy of ritonavir-boosted saquinavir (SQV/r), using the 500-mg filmcoated SQV formulation, in routine clinical pract...
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Article
The influence of HAART on the efficacy and safety of pegylated interferon and ribavirin therapy for the treatment of chronic HCV infection in HIV-positive individuals
This study was performed to investigate the impact of HAART versus no HAART and nucleoside free versus nucleoside containing HAART on the efficacy and safety of pegylated interferon and ribavirin therapy for t...
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Article
Open AccessOnce-daily saquinavir (SAQ)/ritonavir (RTV) (2000/100 mg) with abacavir/lamivudine (600/300 mg) or tenofovir/emtricitabine (245/300 mg) in naïve patients
