22 Result(s)

Article

Disruption of the EGFR E884–R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity

Targeted therapy against epidermal growth factor receptor (EGFR) represents a major therapeutic advance in lung cancer treatment. Somatic mutations of the EGFR gene, most commonly L858R (exon 21) and short in-fra...

Z Tang, S Jiang, R Du, E T Petri, A El-Telbany, P S O Chan, T Kijima… in Oncogene (2009)

Article

Phase II trial of carboplatin plus oral etoposide for elderly patients with small-cell lung cancer

A phase II trial was conducted to evaluate the efficacy and toxicity of the Egorin's carboplatin dosing formula with 14-day oral etoposide in 38 elderly patients with small-cell lung cancer (SCLC). The overall...

K Matsui, N Masuda, M Fukuoka, T Yana, T Hirashima, T Komiya… in British Journal of Cancer (1998)

Article

Information Filtering Using User's Context on Browsing in Hypertext

Browsing is one of the most popular ways to gather information in database with hypertext structure. In order to support a user to browse, modeling of the user's interests is one of the most important issues. ...

T. Hirashima, K. Hachiya, A. Kashihara… in User Modeling and User-Adapted Interaction (1997)

Article

Randomised trial for the prevention of delayed emesis in patients receiving high-dose cisplatin

Despite recent advances in control of acute emesis following cisplatin-based chemotherapy regimens, delayed emesis remains a significant cause of treatment-related morbidity and factors associated with delayed...

K Matsui, M Fukuoka, M Takada, Y Kusunoki, T Yana, K Tamura… in British Journal of Cancer (1996)

Article

Phase I and pharmacologic study of irinotecan in combination with cisplatin for advanced lung cancer

We have conducted a Phase I trial to determine the maximum tolerated dose of CPT-11 together with a fixed dose of cisplatin in patients with advanced lung cancer, and the dose-limiting toxicities of this combi...

N Masuda, M Fukuoka, S Kudoh, Y Kusunoki, K Matsui, N Takifuji… in British Journal of Cancer (1993)

Article

General Lectures

Y. Yamaoka, T. Nagai, K. Furuta, T. Inagawa, T. Sugiya… in Gastroenterologia Japonica (1973)

Article

Postoperative reflux esophagitis with special reference to esophageal manometry and intraluminal pH recording

T. Hara, H. Sato, K. Nabeya, T. Hirashima, A. Shioda… in Gastroenterologia Japonica (1973)

Article

Investigations of surgical therapy for duodenal ulcer by the protein-digestive test tablet

T. Takeshima, H. Sato, T. Hirashima, A. Nishimura, A. Shioda… in Gastroenterologia Japonica (1972)

Article

Surgical experience on the esophageal varices

H. Sato, K. Hirota, Y. Ohtsubo, T. Hirashima, N. Den… in Gastroenterologia Japonica (1970)

Article

Visual observation of the biliary and pancreatic ducts (I) a study on the development of a duodenal fiberscope

H. Satoh, Y. Otsubo, K. Hirota, T. Hirashima, A. Nishimura… in Gastroenterologia Japonica (1969)

Article

A new method of surgical treatment of achalasia esophagocardioplasty with gastric patch

T. Hirashima, H. Sato, K. Hirota, Y. Ohtsubo, N. Den… in Gastroenterologia Japonica (1969)

Article

Esophageal electromyography with intraluminally inserted electrodes

H. Sato, K. Hirota, T. Hirashima, A. Nishimura, M. Sasaki… in Gastroenterologia Japonica (1969)

Article

Experiences on the gastric vagotomy, anterior pexy with pyloroplasty as a treatment for the duodenal ulcer

K. Hirota, H. Sato, M. Odaka, T. Hirashima, A. Nishimura… in Gastroenterologia Japonica (1968)

Article

Histopathological study on achalasia

H. Sato, I. Beniya, K. Hirota, K. Nabeya, T. Hirashima… in Gastroenterologia Japonica (1968)

Article

An experimental development of esophageal achalasia: achalasia-like dogs after the administration of phthalimidomethyl o, o dimethylphosphorodithioate (pmp: cholinesterase inhibitor)

H. Satoh, A. Nishimura, K. Hirota, T. Hirashima… in Gastroenterologia Japonica (1967)

Article

A testing method for digestive function digestive testing ball method

H. Sato, K. Hirota, S. Sakata, Y. Otubo, K. Yamaguchi… in Gastroenterologia Japonica (1967)

Article

Fundamental studies on linear scanning method applied for ri digestion and absorption method

H. Ohkawa, H. Satoh, K. Hirota, Y. Ohtsubo, K. Yamaguchi… in Gastroenterologia Japonica (1967)

Article

Studies on direct gastric hyperthermia (effects on gastroptosis)

Y. Kawaguchi, H. Satoh, M. Ohnishi, H. Takahashi… in Gastroenterologia Japonica (1966)