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Article
Open AccessEfficacy and safety of bemcentinib in patients with advanced myelodysplastic neoplasms or acute myeloid leukemia failing hypomethylating agents- the EMSCO phase II BERGAMO trial
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Chapter
Effective Algebraic Analysis Approach to Linear Systems over Ore Algebras
The purpose of this chapter is to present a survey on the effective algebraic analysis approach to linear systems theory with applications to control theory and mathematical physics. In particular, we show how...
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Article
Risk factors and outcome of graft failure after HLA matched and mismatched unrelated donor hematopoietic stem cell transplantation: a study on behalf of SFGM-TC and SFHI
Graft failure remains a severe complication of hematopoietic stem cell transplantation (HSCT). Several risk factors have already been published. In this study, we re-evaluated them in a large cohort who had th...
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Article
Impact of TP53 mutation variant allele frequency on phenotype and outcomes in myelodysplastic syndromes
Although next-generation sequencing has allowed for the detection of somatic mutations in myelodysplastic syndromes (MDS), the clinical relevance of variant allele frequency (VAF) for the majority of mutations...
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Article
Open AccessTotal genomic alteration as measured by SNP-array-based molecular karyoty** is predictive of overall survival in a cohort of MDS or AML patients treated with azacitidine
Metaphase cytogenetics (MC) has a major role in the risk stratification of patients with myelodysplastic syndromes (MDSs) and can affect the choice of therapies. Azacitidine (AZA) has changed the outcome of pa...
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Chapter and Conference Paper
Symbolic Techniques for Domain Decomposition Methods
Some algorithmic aspects of systems of PDEs based simulations can be better clarified by means of symbolic computation techniques. This is very important since numerical simulations heavily rely on solving sys...
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Article
The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production
In pathological conditions, the amount of DJ-1 determines whether a cell can survive or engage a cell death program. This is exemplified in epithelial cancers, in which DJ-1 expression is increased, while auto...
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Article
Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias
The impact of ten-eleven-translocation 2 (TET2) mutations on response to azacitidine (AZA) in MDS has not been reported. We sequenced the TET2 gene in 86 MDS and acute myeloid leukemia (AML) with 20–30% blasts tr...
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Article
CBFA2T2 and C20orf112: two novel fusion partners of RUNX1 in acute myeloid leukemia
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Article
Pneumoblastoma: a rare lung tumour occurring as a long-term complication after allogeneic haematopoietic cell transplantation
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Article
Que reste-t-il de l’interféron en hématologie ?
Interferon alpha has been investigated in haematology since the end of the 60’s. It may be prescribed in various indications but the availability of the recently developed targeted therapies makes necessary to...
