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Article
Open AccessBeyond prevalence: significance and differential impact of echocardiographic abnormalities in dialysis patients
Echocardiography is commonly used to assess hydratation status and cardiac function in kidney failure patients, but the impact of structural or functional abnormalities on the prognosis of kidney failure patie...
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Article
Open AccessComparison of colistin-induced nephrotoxicity between two different formulations of colistin in critically ill patients: a retrospective cohort study
Colistin is widely used in the treatment of nosocomial infections caused by carbapenem-resistant gram-negative bacilli (CR-GNB). Colistin-induced nephrotoxicity is one of the major adverse reactions during col...
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Article
Open AccessLong-term prognosis of vascular access in hemodialysis patients with systemic lupus erythematosus: a retrospective cohort study
Patients with systemic lupus erythematosus (SLE) have a higher risk of vascular complications. This retrospective cohort study aimed to analyze the differences in the risk of arteriovenous fistula or graft (AV...
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Article
Hereditary bilateral ureteropelvic junction obstruction
A 42-year-old woman presented with hypertensive crisis and bilateral hydronephrosis. She has a strong family history of ureteropelvic junction obstruction. Ureteropelvic junction obstruction is usually sporadi...
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Article
Open AccessAuthor Correction: FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessFHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy
RAAS inhibition has been the standard treatment for CKD for years because it can reduce proteinuria and hence retard renal function decline, but the proteinuria reduction effect is still insufficient in many p...
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Article
Open AccessAssociation between use of oral-antidiabetic drugs and the risk of aortic aneurysm: a nested case–control analysis
Pleiotropic effects on cardiovascular protection have been suggested in several oral antidiabetic drugs (OAD). The impacts of OADs on aortic aneurysm (AA) growth have been found in animal studies, but the evid...
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Open AccessAssociation between previous history of gout attack and risk of deep vein thrombosis - a nationwide population-based cohort study
Although the association of hyperuricemia and cardiovascular diseases is well established by previous research studies, the relationship between gout and deep vein thrombosis (DVT) remains unclear. We conducte...
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Article
Open AccessAssociation between Use of Oral Anti-Diabetic Drugs and the Risk of Sepsis: A Nested Case-Control Study
Although oral antidiabetic drugs (OADs) have been associated with immunomodulation in preclinical studies, little is still known about the association between the use of OADs and the risk of sepsis. Using a co...
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Association of prior antiplatelet agents with mortality in sepsis patients: a nationwide population-based cohort study
Antiplatelet agents are widely used for cardiovascular disea ses, but their pleiotropic effects in sepsis are controversial.
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Article
Effect of the use of low and high potency statins and sepsis outcomes
Although statins have been shown to have cholesterol-lowering effects, their pleiotropic benefits on sepsis remain a matter of debate. In addition, the influence of statin potency on sepsis-related mortality ...
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Article
Open AccessIncidence and outcome of newly-diagnosed tuberculosis in schizophrenics: a 12-year, nationwide, retrospective longitudinal study
To control tuberculosis (TB), it is critical to identify at risk populations. Schizophrenia is recognized as an important risk factor for TB. However, previous studies have been confounded by comorbidities, an...
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Article
Acute Appendicitis in Patients with End-Stage Renal Disease
Acute appendicitis in patients with end-stage renal disease (ESRD) poses a diagnostic challenge. Delayed surgery can contribute to higher morbidity and mortality rates. However, few studies have evaluated this...
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Open AccessEffect of add-on direct renin inhibitor aliskiren in patients with non-diabetes related chronic kidney disease
The renin-angiotensin-aldosterone system (RAAS) plays an important role in the progression of chronic kidney disease (CKD). Although dual RAAS inhibition results in worse renal outcomes than monotherapy in hig...