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Open AccessStudienabschnitt „Vom Symptom zur Erkrankung“ – Schritte in ein integriertes Zahnmedizincurriculum
In Anlehnung an den am Universitätsklinikum Hamburg-Eppendorf bereits etablierten Modellstudiengang Humanmedizin (iMED) wurde das zahnmedizinische Ausbildungskonzept grundlegend überarbeitet und der Modellstud...
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Article
Open AccessEmpagliflozin effects on iron metabolism as a possible mechanism for improved clinical outcomes in non-diabetic patients with systolic heart failure
Sodium-glucose co-transporter-2 (SGLT2) inhibitors improve clinical outcomes in patients with heart failure (HF), but mechanisms of action are incompletely understood. In the EMPA-TROPISM trial, empagliflozin ...
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Article
Open AccessPrevalence and prognostic impact of chronic kidney disease and anaemia across ACC/AHA precursor and symptomatic heart failure stages
The importance of chronic kidney disease (CKD) and anaemia has not been comprehensively studied in asymptomatic patients at risk for heart failure (HF) versus those with symptomatic HF. We analysed the prevale...
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Article
Open AccessAssessment of aortic diameter in Marfan patients: intraindividual comparison of 3D-Dixon and 2D-SSFP magnetic resonance imaging
To compare the accuracy and precision of 3D-Dixon and 2D-SSFP MR-imaging for assessment of aortic diameter in Marfan patients.
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Article
Open AccessThe baroreceptor reflex brought to life outside the classroom – an e-learning based asynchronous laboratory class using a non-supervised modified Active Standing Test
E-learning based laboratory classes can replace or enhance in-classroom laboratories. They typically offer temporal flexibility, self-determined learning speed, repeatability and do not require supervision or ...
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Article
Open AccessSuccess and patient satisfaction of immediately loaded zirconia implants with fixed restorations one year after loading
There is limited evidence for the use of zirconium dioxide implants in immediate implant placement as well as for related immediate loading protocols. The aim of this retrospective study was to investigate the...
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Article
Pharmacological rhythm versus rate control in patients with atrial fibrillation and heart failure: the CASTLE-AF trial
The value of antiarrhythmics to maintain normal sinus rhythm in patients with atrial fibrillation (AF) and heart failure (HF) is still being debated. We aimed to determine whether rhythm control using antiarrh...
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Open AccessClinical Assessment of the Medial Longitudinal Arch in Children: Rater Agreement and Relationship to Objective Foot Arch Measurements
The purpose of this study was to (1) investigate the agreement among clinical experts regarding the classification of the medial longitudinal arch in children and to (2) examine the relationship between the ex...
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Article
Open AccessTeaching About Sexualized Violence in Educational and Clinical Institutions: Evaluation of an Interdisciplinary University Curriculum
Sexualized violence is still a rather avoided topic in teaching at German universities, even though a remarkable proportion of the German population experienced child sexual abuse, including many in institutio...
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Open AccessCorrelation of medical students' situational motivation and performance of non-technical skills during simulation-based emergency training
Non-technical skills (NTS) are an indispensable element of emergency care and need to be prevalent alongside with good technical skills. Though, questions of how to teach (instructional design) and improve NTS...
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Article
Open AccessQuality of life, level of functioning, and its relationship with mental and physical disorders in the elderly: results from the MentDis_ICF65+ study
An ageing population worldwide needs to investigate quality of life (QoL) and level of functioning (LoF) in the elderly and its associated variables. We aimed to study the relationship between Quality of Life ...
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Analysis of outcome for elderly patients after microvascular flap surgery: a monocentric retrospective cohort study
Increasingly, aging societies pose a challenge, particularly in the most developed countries. This trend leads to an increasing group of old and very old patients presenting unique requirements and challenges....
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Open AccessHuman iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model
Human iPSC-derived engineered heart tissue (hEHT) has been used to remuscularize injured hearts in a guinea pig infarction model. While beneficial effects on cardiac remodeling have been demonstrated, the arrh...
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Open AccessExploring sociodemographic subgroup differences in multiple mini-interview (MMI) performance based on MMI station type and the implications for the predictive fairness of the Hamburg MMI
Sociodemographic subgroup differences in multiple mini-interview (MMI) performance have been extensively studied within the MMI research literature, but heterogeneous findings demand a closer look at how speci...
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Article
Open AccessReducing barriers to trauma inquiry in substance use disorder treatment – a cluster-randomized controlled trial
Despite the high rate of traumatic events in clients with substance use disorders, trauma exposure often remains undetected in a majority of treatment-seeking clients. Improving health professionals’ knowledge...
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Article
Post-mortem chemical excitability of the iris should not be used for forensic death time diagnosis
Post-mortem chemical excitability of the iris is one of the non-temperature-based methods in forensic diagnosis of the time since death. Although several authors reported on their findings, using different mea...
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Article
Spinal posture changes using dynamic rasterstereography during the modified Matthiass test discriminate between postural weak and strong healthy children (10–14 years): a pilot study
The aim of this pilot study was to investigate whether the clinical Matthiass test can be objectified by means of dynamic rasterstereography in children. We aimed at discriminating between postural weak and st...
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Article
No difference in the prevalence of Alzheimer-type neurodegenerative changes in the brains of suicides when compared with controls: an explorative neuropathologic study
Suicide ranks among the leading causes of death for individuals of all ages with highest rates in the elderly. The cause of suicide is considered a multifactorial phenomenon. A variety of neurodegenerative dis...
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Open AccessStudy approach and field work procedures of the MentDis_ICF65+ project on the prevalence of mental disorders in the older adult European population
This study describes the study approach and field procedures of the MentDis_ICF65+ study, which aims to assess the prevalence of mental disorders in older adults.
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Post-mortem external examination: competence, education and accuracy of general practitioners in a metropolitan area
In several countries, general practitioners conduct post-mortem external examination (PMEE) and certify death in out-of-hospital cases. A possible lack of accuracy has been repeatedly criticised, although data...
