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Open AccessPerceptions towards biologic and biosimilar therapy of patients with rheumatic and gastroenterological conditions
Biologic and targeted synthetic disease modifying agents (b/tsDMARDs) have broadened the treatment landscape for autoimmune diseases particularly in patients refractory to conventional DMARDs. More recently, t...
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Open AccessUsing the derived 28-joint disease activity score patient-reported components (DAS28-P) index as a discriminatory measure of response to disease-modifying anti-rheumatic drug therapy in early rheumatoid arthritis
The 28-joint disease activity score (DAS28) is a widely used measure to assess disease activity in rheumatoid arthritis (RA). The DAS28-P index, a derived proportion of the patient-reported components (joint t...
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Article
Open AccessSleep disorders and gout in Australian adults
The aims of our study were two-fold. Firstly, to determine if there is an association between gout and OSA in a representative Australian adult population. Secondly, to explore associations between gout and pa...
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Article
Open AccessIFNL3 genotype is associated with pulmonary fibrosis in patients with systemic sclerosis
Fibrosis across different organs and tissues is likely to share common pathophysiological mechanisms and pathways. Recently, a polymorphism (rs12979860) near the interferon lambda gene (IFNL3) was shown to be ass...
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Article
Open AccessThe utility of ESR, CRP and platelets in the diagnosis of GCA
To compare the utility of ESR, CRP and platelets for the diagnosis of GCA.
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Open AccessGout prevalence and predictors of urate-lowering therapy use: results from a population-based study
Gout has an increasing global prevalence. Underutilization of urate-lowering therapy (ULT) is thought to be common, via both suboptimal dosing and poor medication adherence. The aims of this study were to dete...
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Open AccessFactors associated with oral glucocorticoid use in patients with rheumatoid arthritis: a drug use study from a prospective national biologics registry
Glucocorticoids (GCs) are used in ~ 60% of patients with rheumatoid arthritis (RA). Although disease-modifying, they also have significant adverse effects. Understanding factors associated with GC use may help...
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Article
Erratum to: Papilloma on Core Biopsy: Excision vs. Observation
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Papilloma on Core Biopsy: Excision vs. Observation
Intraductal papillomas (IPs) are commonly seen breast lesions with variable clinical presentation. For a palpable lesion and/or evidence of cellular atypia and/or pathologic nipple discharge, excision is warra...
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Open AccessA comparison of the predictive accuracy of three screening models for pulmonary arterial hypertension in systemic sclerosis
There is evidence that early screening for pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc) improves outcomes. We compared the predictive accuracy of two recently published screening algorithm...
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Open AccessThe inclusion of N-terminal pro-brain natriuretic peptide in a sensitive screening strategy for systemic sclerosis-related pulmonary arterial hypertension: a cohort study
Pulmonary arterial hypertension (PAH) is a major cause of mortality in systemic sclerosis (SSc). Screening guidelines for PAH recommend multiple investigations, including annual echocardiography, which togethe...
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Open AccessEpistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome
The aim of this study was to examine the association between functional polymorphisms in the pro-inflammatory P2X7 receptor and the Ro/La autoantibody response in primary Sjögren's syndrome (pSS).
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The incidence and associations of malignancy in a large cohort of patients with biopsy-determined idiopathic inflammatory myositis
The South Australian (SA) myositis database has registered all patients with biopsy-proven inflammatory myositis in SA from 1980 to 2009. We determined the incidence and associations of malignancy in myositis ...
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Zinc-rich inhibitor of apoptosis proteins (IAPs) as regulatory factors in the epithelium of normal and inflamed airways
Integrity of the airway epithelium (AE) is important in the context of inhaled allergens and noxious substances, particularly during asthma-related airway inflammation where there is increased vulnerability of...
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Open AccessFactor structure and validity of the shoulder pain and disability index in a population-based study of people with shoulder symptoms
The Shoulder Pain and Disability Index (SPADI) is a self-administered questionnaire that aims to measure pain and disability associated with shoulder disease. The aim of the present study was to investigate th...
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CTLA4 polymorphism and primary Sjögren's syndrome
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Extensive genomic and functional polymorphism of the complement control proteins
Using combinations of genomic markers, we describe more than 20 distinct ancestral haplotypes (AH) of complement control proteins (CCPs), located within the regulators of complement activation (RCA) alpha bloc...