Skip to main content

and
  1. Article

    Open Access

    Perceptions towards biologic and biosimilar therapy of patients with rheumatic and gastroenterological conditions

    Biologic and targeted synthetic disease modifying agents (b/tsDMARDs) have broadened the treatment landscape for autoimmune diseases particularly in patients refractory to conventional DMARDs. More recently, t...

    Thomas Khoo, Navkiran Sidhu, Franca Marine, Susan Lester in BMC Rheumatology (2022)

  2. Article

    Open Access

    Using the derived 28-joint disease activity score patient-reported components (DAS28-P) index as a discriminatory measure of response to disease-modifying anti-rheumatic drug therapy in early rheumatoid arthritis

    The 28-joint disease activity score (DAS28) is a widely used measure to assess disease activity in rheumatoid arthritis (RA). The DAS28-P index, a derived proportion of the patient-reported components (joint t...

    Huai Leng Pisaniello, Samuel L. Whittle, Susan Lester, Fiona Menz in BMC Rheumatology (2022)

  3. Article

    Open Access

    Sleep disorders and gout in Australian adults

    The aims of our study were two-fold. Firstly, to determine if there is an association between gout and OSA in a representative Australian adult population. Secondly, to explore associations between gout and pa...

    Julia New-Tolley, Amy C. Reynolds, Sarah L. Appleton, Tiffany K. Gill in BMC Rheumatology (2021)

  4. Article

    Open Access

    IFNL3 genotype is associated with pulmonary fibrosis in patients with systemic sclerosis

    Fibrosis across different organs and tissues is likely to share common pathophysiological mechanisms and pathways. Recently, a polymorphism (rs12979860) near the interferon lambda gene (IFNL3) was shown to be ass...

    Mayada Metwally, Khaled Thabet, Ali Bayoumi, Mandana Nikpour in Scientific Reports (2019)

  5. Article

    Open Access

    The utility of ESR, CRP and platelets in the diagnosis of GCA

    To compare the utility of ESR, CRP and platelets for the diagnosis of GCA.

    Fiona Li Ying Chan, Susan Lester, Samuel Lawrence Whittle in BMC Rheumatology (2019)

  6. Article

    Open Access

    Gout prevalence and predictors of urate-lowering therapy use: results from a population-based study

    Gout has an increasing global prevalence. Underutilization of urate-lowering therapy (ULT) is thought to be common, via both suboptimal dosing and poor medication adherence. The aims of this study were to dete...

    Huai Leng Pisaniello, Susan Lester, David Gonzalez-Chica in Arthritis Research & Therapy (2018)

  7. Article

    Open Access

    Factors associated with oral glucocorticoid use in patients with rheumatoid arthritis: a drug use study from a prospective national biologics registry

    Glucocorticoids (GCs) are used in ~ 60% of patients with rheumatoid arthritis (RA). Although disease-modifying, they also have significant adverse effects. Understanding factors associated with GC use may help...

    Rachel J. Black, Susan Lester, Rachelle Buchbinder in Arthritis Research & Therapy (2017)

  8. Article

    Erratum to: Papilloma on Core Biopsy: Excision vs. Observation

    Faina Nakhlis, Nasim Ahmadiyeh, Susan Lester, Sughra Raza in Annals of Surgical Oncology (2015)

  9. No Access

    Article

    Papilloma on Core Biopsy: Excision vs. Observation

    Intraductal papillomas (IPs) are commonly seen breast lesions with variable clinical presentation. For a palpable lesion and/or evidence of cellular atypia and/or pathologic nipple discharge, excision is warra...

    Faina Nakhlis, Nasim Ahmadiyeh, Susan Lester, Sughra Raza in Annals of Surgical Oncology (2015)

  10. Article

    Open Access

    A comparison of the predictive accuracy of three screening models for pulmonary arterial hypertension in systemic sclerosis

    There is evidence that early screening for pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc) improves outcomes. We compared the predictive accuracy of two recently published screening algorithm...

    Yanjie Hao, Vivek Thakkar, Wendy Stevens in Arthritis Research & Therapy (2015)

  11. Article

    Open Access

    The inclusion of N-terminal pro-brain natriuretic peptide in a sensitive screening strategy for systemic sclerosis-related pulmonary arterial hypertension: a cohort study

    Pulmonary arterial hypertension (PAH) is a major cause of mortality in systemic sclerosis (SSc). Screening guidelines for PAH recommend multiple investigations, including annual echocardiography, which togethe...

    Vivek Thakkar, Wendy Stevens, David Prior, Peter Youssef in Arthritis Research & Therapy (2013)

  12. Article

    Open Access

    Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome

    The aim of this study was to examine the association between functional polymorphisms in the pro-inflammatory P2X7 receptor and the Ro/La autoantibody response in primary Sjögren's syndrome (pSS).

    Susan Lester, Leanne Stokes, Kristen K Skarratt, Ben J Gu in Arthritis Research & Therapy (2013)

  13. No Access

    Article

    The incidence and associations of malignancy in a large cohort of patients with biopsy-determined idiopathic inflammatory myositis

    The South Australian (SA) myositis database has registered all patients with biopsy-proven inflammatory myositis in SA from 1980 to 2009. We determined the incidence and associations of malignancy in myositis ...

    Vidya Limaye, Colin Luke, Graeme Tucker, Catherine Hill in Rheumatology International (2013)

  14. No Access

    Article

    Zinc-rich inhibitor of apoptosis proteins (IAPs) as regulatory factors in the epithelium of normal and inflamed airways

    Integrity of the airway epithelium (AE) is important in the context of inhaled allergens and noxious substances, particularly during asthma-related airway inflammation where there is increased vulnerability of...

    Eugene Roscioli, Rhys Hamon, Susan Lester, Chiara Murgia, Janet Grant in BioMetals (2013)

  15. Article

    Open Access

    Factor structure and validity of the shoulder pain and disability index in a population-based study of people with shoulder symptoms

    The Shoulder Pain and Disability Index (SPADI) is a self-administered questionnaire that aims to measure pain and disability associated with shoulder disease. The aim of the present study was to investigate th...

    Catherine L Hill, Susan Lester, Anne W Taylor in BMC Musculoskeletal Disorders (2011)

  16. Article

    CTLA4 polymorphism and primary Sjögren's syndrome

    Susan Lester, Sarah Downie-Doyle, Maureen Rischmueller in Arthritis Research & Therapy (2007)

  17. No Access

    Article

    Extensive genomic and functional polymorphism of the complement control proteins

    Using combinations of genomic markers, we describe more than 20 distinct ancestral haplotypes (AH) of complement control proteins (CCPs), located within the regulators of complement activation (RCA) alpha bloc...

    Craig A. McLure, Joseph F. Williamson, Louise A. Smyth, Suraksha Agrawal in Immunogenetics (2005)