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  1. Article

    Open Access

    Ultrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas

    Given the marginal penetration of most drugs across the blood-brain barrier, the efficacy of various agents remains limited for glioblastoma (GBM). Here we employ low-intensity pulsed ultrasound (LIPU) and int...

    Víctor A. Arrieta, Andrew Gould, Kwang-Soo Kim, Karl J. Habashy in Nature Communications (2024)

  2. Article

    Open Access

    A pairwise cytokine code explains the organism-wide response to sepsis

    Sepsis is a systemic response to infection with life-threatening consequences. Our understanding of the molecular and cellular impact of sepsis across organs remains rudimentary. Here, we characterize the path...

    Michihiro Takahama, Ashwini Patil, Gabriella Richey, Denis Cipurko in Nature Immunology (2024)