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  1. Article

    Open Access

    Overexpression of Atg5 in mice activates autophagy and extends lifespan

    Autophagy has been implicated in the ageing process, but whether autophagy activation extends lifespan in mammals is unknown. Here we show that ubiquitous overexpression of Atg5, a protein essential for autoph...

    Jong-Ok Pyo, Seung-Min Yoo, Hye-Hyun Ahn, Jihoon Nah, Se-Hoon Hong… in Nature Communications (2013)

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