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Sunmin Jung
Life Sciences
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Article
Open AccessPhosphorylated CAV1 activates autophagy through an interaction with BECN1 under oxidative stress
CAV1/Caveolin1, an integral membrane protein, is involved in caveolae function and cellular signaling pathways. Here, we report that CAV1 is a positive regulator of autophagy under oxidative stress and cerebra...
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Article
OCIAD2 activates γ-secretase to enhance amyloid β production by interacting with nicastrin
The gamma (γ)-secretase holoenzyme is composed of four core proteins and cleaves APP to generate amyloid beta (Aβ), a key molecule that causes major neurotoxicity during the early stage of Alzheimer’s disease ...
