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  1. Article

    Open Access

    Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice

    Hypercholesterolemia and vascular inflammation are key interconnected contributors to the pathogenesis of atherosclerosis. How hypercholesterolemia initiates vascular inflammation is poorly understood. Here we...

    Liming Yu, Lin Xu, Haiyan Chu, Jun Peng, Anastasia Sacharidou in Nature Communications (2023)

  2. Article

    Open Access

    Clinical impact of and microbiological risk factors for qacA/B positivity in ICU-acquired ST5-methicillin-resistant SCCmec type II Staphylococcus aureus bacteremia

    Concern about resistance to chlorhexidine has increased due to the wide use of the latter. The impact of the qacA/B and smr chlorhexidine tolerance genes on the outcome of methicillin-resistant Staphylococcus aur...

    Haein Kim, Sunghee Park, Hyeonji Seo, Hyemin Chung, Eun Sil Kim in Scientific Reports (2022)

  3. Article

    Open Access

    CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer

    Tumor-associated myeloid cells regulate tumor growth and metastasis, and their accumulation is a negative prognostic factor for breast cancer. Here we find calcium/calmodulin-dependent kinase kinase (CaMKK2) t...

    Luigi Racioppi, Erik R. Nelson, Wei Huang, Debarati Mukherjee in Nature Communications (2019)