12 Result(s)
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Article
Open AccessTafamidis decreased cardiac amyloidosis deposition in patients with Ala97Ser hereditary transthyretin cardiomyopathy: a 12-month follow-up cohort study
Transthyretin cardiac cardiomyopathy (ATTR-CM) is a rare but life-threatening disease. Tafamidis is an effective treatment for patients with ATTR-CM, however its long-term effects on cardiac remodeling and car...
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Article
Open AccessRU-Net: skull strip** in rat brain MR images after ischemic stroke with rat U-Net
Experimental ischemic stroke models play a fundamental role in interpreting the mechanism of cerebral ischemia and appraising the development of pathological extent. An accurate and automatic skull strip** t...
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Chapter
Overview of Small Fiber Neuropathy
Small fiber neuropathy (SFN) results from impairment of small-diameter myelinated Aδ- and unmyelinated C-fibers. This debilitating condition usually leads to alterations in nociceptive processing, thermal sens...
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Chapter
Small Fiber Pathology and Functional Impairment in Syndromes of Predominantly Large Fiber Neuropathy
In peripheral neuropathies with sensory ataxia or weakness of distal limbs, traditionally nerve conduction studies are the first-line tests, and these neuropathies are classified as large fiber neuropathy incl...
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Chapter
Neuropathic Pain in Small Fiber Neuropathy
Neuropathic pain is the most common and disabling symptom in small fiber neuropathy (SFN). It usually presents as a burning or tingling sensation in the distal limbs, accompanied by increased pain sensitivity,...
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Chapter
Amyloid Neuropathy
Amyloid neuropathy is a syndrome of peripheral nerve degeneration associated with deposition of amyloid attributed to various molecular compositions including (1) monoclonal protein of immunoglobulin light cha...
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Article
Open AccessQuality of life in polyneuropathy: association with biomarkers of small fiber impairment
Polyneuropathy presumably lowers quality of life (QoL). However, there is a lack of systematic studies that assess QoL changes and biomarkers of polyneuropathy as determinants of QoL. We aimed to investigate t...
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Article
Open AccessMitochondrial fission augments capsaicin-induced axonal degeneration
Capsaicin, an agonist of transient receptor potential vanilloid receptor 1, induces axonal degeneration of peripheral sensory nerves and is commonly used to treat painful sensory neuropathies. In this study, w...
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Article
Open AccessRole of acid-sensing ion channel 3 in sub-acute-phase inflammation
Inflammation-mediated hyperalgesia involves tissue acidosis and sensitization of nociceptors. Many studies have reported increased expression of acid-sensing ion channel 3 (ASIC3) in inflammation and enhanced ...
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Article
Characterization of a familial case with primary erythromelalgia from Taiwan
Familial primary erythromelalgia is a rare autosomal dominant disease characterized by redness and painful episodes of the feet and hands, which is often triggered by heat or exercise. In this report, a Taiwan...
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Reference Work Entry In depth
Toxic Neuropathies
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Article
Quantitative pathology of cutaneous nerve terminal degeneration in the human skin
Pathological diagnosis of neuropathy has traditionally depended on ultrastructural examinations of nerve biopsy specimens, particularly for sensory neuropathies affecting unmyelinated and small-myelinated noc...
