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  1. Article

    Open Access

    COX17 acetylation via MOF–KANSL complex promotes mitochondrial integrity and function

    Reversible acetylation of mitochondrial proteins is a regulatory mechanism central to adaptive metabolic responses. Yet, how such functionally relevant protein acetylation is achieved remains unexplored. Here ...

    Sukanya Guhathakurta, Niyazi Umut Erdogdu, Juliane J. Hoffmann… in Nature Metabolism (2023)

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  2. Article

    Author Correction: The NSL complex maintains nuclear architecture stability via lamin A/C acetylation

    Adam Karoutas, Witold Szymanski, Tobias Rausch, Sukanya Guhathakurta… in Nature Cell Biology (2023)

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  3. No Access

    Article

    Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature

    Mutations in chromatin-modifying complexes and metabolic enzymes commonly underlie complex human developmental syndromes affecting multiple organs. A major challenge is to determine how disease-causing genetic...

    Bilal N. Sheikh, Sukanya Guhathakurta, Tsz Hong Tsang… in Nature Cell Biology (2020)

  4. No Access

    Article

    The NSL complex maintains nuclear architecture stability via lamin A/C acetylation

    While nuclear lamina abnormalities are hallmarks of human diseases, their interplay with epigenetic regulators and precise epigenetic landscape remain poorly understood. Here, we show that loss of the lysine a...

    Adam Karoutas, Witold Szymanski, Tobias Rausch, Sukanya Guhathakurta… in Nature Cell Biology (2019)