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Multi-omics in Study of Lung Microbiome
The lung microbiome influences the pathophysiology of pulmonary diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. The advancement of sequencing technologies, such a...
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Article
Genome-wide identification and annotation of SNPs for economically important traits in Frieswal™, newly evolved crossbred cattle of India
The Frieswal™ is a crossbred cattle evolved by ICAR-Central Institute for Research on Cattle utilizing more than 15,000 cattle maintained at more than 37 military farms spread all over the agro-climatic region...
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Chapter
Infectious Pulmonary Diseases
Different infectious pathogens like viruses, bacteria, and in rare occasion fungi infect the human respiratory tract leading to the onset of upper and lower respiratory tract infections. Infectious pulmonary d...
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Chapter
Obstructive Airway Diseases
Asthma, COPD (including chronic bronchitis and emphysema), and bronchiectasis are the commonly encountered obstructive airway diseases. Symptomatic similarity across the different obstructive airway diseases m...
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Chapter
Restrictive Pulmonary Diseases
Restrictive pulmonary diseases refers to “a group of lung disorders associated with restricted lung expansion and reduced lung volume”. These pulmonary diseases can ensue from intrinsic parenchymal pathologies...
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Protocol
Computational Vaccine Design for Common Allergens
In this chapter, the steps of designing candidate vaccine molecules for allergen-specific immunotherapy (AIT) using immunoinformatics are described. The most modern approach of AIT deals with carrier-bound B c...
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Protocol
Updates on Databases of Allergens and Allergen-Epitopes
The increasing prevalence of allergic diseases is of great public health concern. Environmental and food allergens are the major triggers of allergic diseases via respiratory or gastrointestinal routes, respec...
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Chapter
Pulmonary Vascular Diseases
Pulmonary vascular diseases or pulmonary vasculopathies represent diseases of pulmonary vasculature that are associated with altered pulmonary vascular resistance and compromised pulmonary circulation. The eti...
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Chapter
COVID-19
The global viral pandemic of COVID-19, caused by SARS-CoV-2 created an unprecedented demand for rapid diagnosis, containment, and treatment of the disease. However, the diverse clinical presentation of COVID-1...
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Chapter
Lung Cancer
Lung cancer has a complex pathophysiology and is one of the leading causes of death all over the world. Cutting edge imaging modalities and omics approaches have improved the diagnosis, stratification, and sta...
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Chapter
Asthma
Cutting edge omics approaches have led to phenoty** and sub-phenoty** of asthma based on underlying molecular endotypes. T2-high and T2-low asthma have been widely recognized. Differential airway immune re...
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Chapter
Sarcoidosis
The complex, heterogeneous clinical presentation of sarcoidosis leads to misdiagnosis and delayed initialization of treatment. Recent advancement in omics approaches has boosted biomarker research and improved...
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Book
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Chapter
Pulmonary Hypertension
The progressive and devastating disorder of pulmonary hypertension is associated with vascular remodelling and vascular rarefaction. This escalates pulmonary arterial pressures and pulmonary vascular resistanc...
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Chapter
Tuberculosis
Tuberculosis is one of the major global health concerns associated with a high morbidity and mortality rate. Pulmonary tuberculosis may remain latent or manifest in the form of severe respiratory tract infecti...
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Chapter
Pneumonia
Pneumonia is an acute lower respiratory tract infection affecting the bronchioles, alveoli, and distal airways. Such infections are primarily caused by bacteria, viruses, and mycoplasma, but may also be caused...
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Chapter
Introduction to Pulmonary Diseases and OMICS Approaches
Incidence of diseases affecting the respiratory tract and lungs have increased in the past few decades. Exposure to harmful environmental triggers, infections, genetic factors, and aging contributes to progres...
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Chapter
Chronic Obstructive Pulmonary Disease (COPD)
Effective COPD diagnosis and disease stratification is largely hindered due to presence of symptomatic similarity with other lung diseases and presence of comorbidities. Several probable biomarker candidates h...
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Chapter
Bronchiectasis
Bronchiectasis is an obstructive airway disease characterized by persistent bronchial dilation, defective mucociliary clearance, and recurrent microbial infections. Medical imaging and radiomics find an enormo...
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Chapter
Idiopathic Pulmonary Fibrosis
The unknown aetiology of irreversible fibrotic scarring of lung tissues in Idiopathic Pulmonary Fibrosis (IPF) has resulted in the lack of a gold standard for disease diagnosis. Presently, medical imaging like...
