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Fluorescence Spectroscopy: A Useful Method to Explore the Interactions of Small Molecule Ligands with DNA Structures

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  1. Article

    Open Access

    Theranostic approach to specifically targeting the interloop region of BCL2 i-motif DNA by crystal violet

    Ligands that recognise specific i-motif DNAs are helpful in cancer diagnostics and therapeutics, as i-motif formation can cause cancer. Although the loop regions of i-motifs are promising targets for ligands, ...

    Sinjan Das, Shuntaro Takahashi, Tatsuya Ohyama, Sudipta Bhowmik… in Scientific Reports (2023)

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  2. Article

    Open Access

    Preferential targeting cancer-related i-motif DNAs by the plant flavonol fisetin for theranostics applications

    The relationship of i-motif DNAs with cancer has prompted the development of specific ligands to detect and regulate their formation. Some plant flavonols show unique fluorescence and anti-cancer properties, w...

    Shuntaro Takahashi, Snehasish Bhattacharjee, Saptarshi Ghosh… in Scientific Reports (2020)

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