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Open AccessInhibition of nuclear factor κB in the lungs protect bleomycin-induced lung fibrosis in mice
Pulmonary fibrosis is a debilitating condition with limited therapeutic avenues. The pathogenicity of pulmonary fibrosis constitutes involvement of cellular proliferation, activation, and transformational chan...
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Article
Retraction Note: Role of the NF-κB signaling cascade and NF-κB-targeted genes in failing human hearts
The Editor-in-Chief has retracted this article [1] because a number of lanes in Figs. 3, 4 and 6 of this article are duplicated.
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Correction to: Modulation of miRNA in Oxidative Stress-Induced Cardiac Remodeling
The figure legends of Figs. 3.2 and 3.3 of this chapter were swapped inadvertently and published with errors. The correct presentation is given here.
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Modulation of miRNA in Oxidative Stress-Induced Cardiac Remodeling
Cardiac remodeling is the pathological ramification of myocardium resulting into various cardiac diseases. Oxidative stress represents a self-perpetuating mechanism by producing excess reactive oxygen species ...
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Article
S100A8/MYD88/NF-қB: a novel pathway involved in cardiomyocyte hypertrophy driven by thyroid hormone
Recent studies have evidenced the involvement of inflammation-related pathways to the development of cardiac hypertrophy and other consequences on the cardiovascular system, including the calcium-binding prote...
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NF-κB-mediated miR-30b regulation in cardiomyocytes cell death by targeting Bcl-2
Angiotensin II(Ang II)-stimulated cardiomyocytes hypertrophy and apoptosis are associated with nuclear factor-κB (NF-κB) activation. NF-κB, a redox-sensitive transcription factor, contributes a critical role i...
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Circulating miRNA as novel markers for diastolic dysfunction
MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate gene expression. Though their significance is unclear, pioneer profiling studies have attributed specific serum miRNA signatures to differen...
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Article
Nuclear localization of Myomesin-1: possible functions
Myomesin-I (also known as Skelemin) is a ~185 kDa protein, which is highly expressed in striated muscle. It contains the prototypic class-I (type-III fibronectin) and class-II (C2-immunoglobulin) motifs. Previ...
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Article
Upregulation of lysyl oxidase and MMPs during cardiac remodeling in human dilated cardiomyopathy
Objective Dilated cardiomyopathy (DCM) represents a large subset of patients with congestive heart failure (HF), and myocardial fibrosis has been shown to be associated with this process. Lysyl oxidase (LOX), a k...
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Animal Models for Heart Failure
Heart failure (HF) is a major cause of morbidity and mortality worldwide. Although many therapeutic means are available to prolong the life of HF patients, why HF develops is still poorly understood. Investiga...
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Article
Open AccessAn ABRE-binding factor, OSBZ8, is highly expressed in salt tolerant cultivars than in salt sensitive cultivars of indica rice
The bZIP class Abscisic acid Responsive Element (ABRE)-binding factor, OSBZ8 (38.5 kD) has been considered to regulate ABA-mediated transcription in the suspension cultured cells of japonica rice. Still, nothi...
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RETRACTED ARTICLE: Role of the NF-κB signaling cascade and NF-κB-targeted genes in failing human hearts
Nuclear factor-κB (NF-κB) is a ubiquitous transcription factor that has been indicated to play a causal role for many pathological states. Heart failure is a major cause of morbidity all over the world. In thi...
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Article
Regulation of myotrophin gene by pressure overload and stretch
Hemodynamic load is a major determinant of cardiac mass and its phenotype, but very little is known about how mechanical load is converted into intracellular signals of gene expression and regulation. We have ...
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Airborne pollen of Borassus flabellifer: Quantification of allergen and antigen
Airborne pollen grains of Borassus flabellifer were recorded at Madhyamgram, during February to June 1995–1996 commensurate with the plants flowering season. The following year (1996–1997), the exposed Burkard...
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Expression of abscisic acid-responsive element-binding protein in salt-tolerant indica rice (it Oryza sativa L. cv. Pokkali)
As the products of abiotic stress and ABA inducible genes are predicted to play an important role in the mechanism of salt tolerance, the expression of transcription factor that recognizes abscisic acid-respon...
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Expression of arginine decarboxylase in seedlings of indica rice (Oryza sativa L.) cultivars as affected by salinity stress
The effect of salinity stress on the activity of arginine decarboxylase (ADC, EC 4.1.1.19), the first enzyme in biosynthesis of polyamines (PA) from arginine, as well as its transcript level has been compared ...
