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Article
The Effects of HFE Polymorphisms on Biochemical Parameters of Iron Status in Arab Beta-Thalassemia Patients
In this study, the potential effect of three HFE gene polymorphisms (C282Y, H63D and S65C) and the SLC40A1 A77D polymorphism on iron balance was investigated in 234 subjects (91 Arab beta-thalassemia major (BTM) ...
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Article
Influence of MX1 promoter rs2071430 G/T polymorphism on susceptibility to systemic lupus erythematosus
The expression of interferon inducible genes are reported to be heightened in systemic lupus erythematosus (SLE); nevertheless, not much is known regarding the genetic variants underlying these genes and their...
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Article
Characterization of drug-metabolizing enzymes CYP2C9, CYP2C19 polymorphisms in Tunisian, Kuwaiti and Bahraini populations
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Article
Violating the Theory of Single Gene-Single Disorder: Inhibitor Development in Hemophilia
Hemophilia is clinically and genetically heterogeneous blood disorder with several known gene defects accounting for the diversity of disease phenotype and inhibitor production. Although increasing number of c...
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Article
Genetic analysis of interleukin-1 receptor antagonist and interleukin-1β single-nucleotide polymorphisms C−511T and C+3953T in alopecia areata: susceptibility and severity association
The present study was aimed to explore the effect of two selected polymorphisms from interleukin-1β (IL-1β) gene [SNPs −511 and +3953] and a variable number of tandem repeat (VNTR) from interleukin-1 receptor ...
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Article
Association of Hashimoto’s thyroiditis with cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) and inducible co-stimulator (ICOS) genes in a Kuwaiti population
Analysing two CTLA-4 markers [exon 1 A49G single nucleotide polymorphism (SNP) and exon 4 3′UTR (AT)n repeat] and the ICOS intron 4 (GT)n marker for their potential association with HT, and exploring the effect o...
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Article
Lack of Association of NOS3 and ACE Gene Polymorphisms with Coronary Artery Disease in Southern Tunisia
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Article
Allele Frequency Distribution Data for D8S1132, D8S1779, D8S514, and D8S1743 in Four Ethnic Groups in Relation to Metabolic Syndrome: Tehran Lipid and Glucose Study