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  1. Article

    Open Access

    Effect of di-(2-ethylhexyl) phthalate (DEHP) on allergic rhinitis

    Allergic rhinitis (AR) is a common chronic inflammatory disease of the upper respiratory tract. Di(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer and belongs to environmental endocrine disruptors ...

    Qi-Yuan Zou, Su-Ling Hong, Hou-Yong Kang, **a Ke, **ao-Qiang Wang… in Scientific Reports (2020)

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  2. Article

    Open Access

    The airway inflammation induced by nasal inoculation of PM2.5 and the treatment of bacterial lysates in rats

    Particulate matter (PM) is one of the most important environmental issues in China. This study aimed to explore the correlation between PM2.5 and airway inflammation in healthy rats. The PM2.5 group was given ...

    Yang Shen, Zhi-Hai Zhang, Di Hu, **a Ke, Zheng Gu, Qi-Yuan Zou… in Scientific Reports (2018)

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  3. No Access

    Article

    MicroRNA expression profile of mature dendritic cell in chronic rhinosinusitis

    Chronic rhinosinusitis (CRS), which includes CRS without nasal polyposis (CRSsNP) and with nasal polyposis (CRSwNP), shows imbalance of helper T cells (Th) and regulatory T cells (Treg). The balance of Th and ...

    Zu-**a Ma, ** Tan, Yang Shen, **a Ke, Yu-Cheng Yang, **ng-Bo He… in Inflammation Research (2015)

  4. Article

    Erratum to: Association study between interleukin-12 receptor β1/β2 genes and allergic rhinitis in the Chinese Han population

    ** Wei, Wei Kou, Rong Sun, Guo-hua Hu… in European Archives of Oto-Rhino-Laryngology (2015)

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  5. No Access

    Article

    Association study between interleukin-12 receptor β1/β2 genes and allergic rhinitis in the Chinese Han population

    Interleukin-12 (IL-12) plays a key role in the protection against allergic reaction induced by allergen as well as the differentiation of T helper 1 cells in patients with allergic rhinitis (AR), exerting its ...

    ** Wei, Wei Kou, Rong Sun, Guo-hua Hu… in European Archives of Oto-Rhino-Laryngology (2015)

  6. No Access

    Article

    Andrographolide Suppresses IL-6/Stat3 Signaling in Peripheral Blood Mononuclear Cells from Patients with Chronic Rhinosinusitis with Nasal Polyps

    The mechanisms underlying the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) remain largely unknown. CRSwNP has garnered considerable public health concern owing to its high incidence and un...

    Wei Kou, Rong Sun, ** Wei, Hong-Bing Yao, Cheng Zhang, **n-Ye Tang… in Inflammation (2014)

  7. No Access

    Article

    Role of the Aryl Hydrocarbon Receptor in the Pathogenesis of Chronic Rhinosinusitis with Nasal Polyps

    A predominant Th17 population is a marker of chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients. As a ligand-activated transcription factor, the aryl hydrocarbon receptor (AhR) plays a vital...

    ** Wei, Guo-hua Hu, Hou-yong Kang, Hong-bing Yao, Wei Kou, Cheng Zhang… in Inflammation (2014)

  8. No Access

    Article

    Transforming growth factor-β1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment

    A predominant Th17 population and impaired Treg function is the marker of nasal polyposis (NP) in Chinese patients. TGF-β1, a multifunction cytokine, is a vital factor involved in inducing or restricting speci...

    Wei Kou, Guo-Hua Hu, Hong-Bing Yao, **ao-Qiang Wang, Yang Shen… in Inflammation Research (2013)

  9. No Access

    Article

    EBV-LMP1-targeted DNAzyme restrains nasopharyngeal carcinoma growth in a mouse C666-1 xenograft model

    Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) has been demonstrated to be linked to the pathogenesis of nasopharyngeal carcinoma (NPC), one of the most common cancers in southeast Asia as w...

    **a Ke, Yu-cheng Yang, Su-ling Hong in Medical Oncology (2011)