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Article
Open AccessInflammation and vascular remodeling in COVID-19 hearts
A wide range of cardiac symptoms have been observed in COVID-19 patients, often significantly influencing the clinical outcome. While the pathophysiology of pulmonary COVID-19 manifestation has been substantia...
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Article
Open AccessAltered generation of ciliated cells in chronic obstructive pulmonary disease
In COPD, epithelial changes are prominent features in the airways, such as goblet cell hyperplasia and squamous metaplasia. In contrast, it remains unclear whether ciliated cells are reduced and which pathways...
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Lung Allograft Dysfunction (LAD) and Bronchiolitis Obliterans Syndrome
Lung transplantation is currently considered as an ultimate lifesaving treatment for selected patients suffering from end-stage pulmonary disease. Long-term survival, however, is hampered by chronic rejection,...
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Article
Healthy brain ageing assessed with 18F-FDG PET and age-dependent recovery factors after partial volume effect correction
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BMPRII influences the response of pulmonary microvascular endothelial cells to inflammatory mediators
Mutations in the bone morphogenetic protein receptor (BMPR2) gene have been observed in 70 % of patients with heritable pulmonary arterial hypertension (HPAH) and in 11–40 % with idiopathic PAH (IPAH). However, c...
