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Chapter
Mechanisms Controlling Steroid Receptor Binding to Specific DNA Sequences
The biological actions of steroid hormones are mediated by specific nuclear receptors to regulate an increase or decrease in transcription of specific genes and thereby exert their influence on development and...
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Article
Modulators of cellular protein phosphorylation alter thetrans-activation function of human progesterone receptor and the biological activity of progesterone antagonists
Addition of progesterone to breast cancer cellsin vivo increases phosphorylation of human progesterone receptor (PR), suggesting that phosphorylation has a regulatory role in producing the activated form of recep...
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Article
Open AccessClaudin 7 expression and localization in the normal murine mammary gland and murine mammary tumors
Claudins, membrane-associated tetraspanin proteins, are normally associated with the tight junctions of epithelial cells where they confer a variety of permeability properties to the transepithelial barrier. O...
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Article
Endocrine Disrupting Activities of the Flavonoid Nutraceuticals Luteolin and Quercetin
Dietary plant flavonoids have been proposed to contribute to cancer prevention, neuroprotection, and cardiovascular health through their anti-oxidant, anti-inflammatory, pro-apoptotic, and antiproliferative ac...