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  1. No Access

    Chapter

    New Aspects of DNA Adduct Formation by the Carcinogens Crotonaldehyde and Acetaldehyde

    Crotonaldehyde and acetaldehyde are mutagenic in S. typhimurium and other systems used for detection of genetic damage (IARC, 1985; 1995; 1999). Crotonaldehyde induces altered liver cell foci, neoplastic nodules,...

    Stephen S. Hecht, Edward J. McIntee, Guang Cheng… in Biological Reactive Intermediates VI (2001)

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    Book

    Nitroarenes

    Occurrence, Metabolism, and Biological Impact

    Paul C. Howard, Stephen S. Hecht, Frederick A. Beland in Environmental Science Research (1990)

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    Chapter

    Products Obtained by in Vitro Reaction of 4, 5-Epoxy-4, 5-Dihydro-1-Nitropyrene with DNA

    A number of nitropolycyclic aromatic hydrocarbons (NO2-PAH) have been identified in environmental sources(1–3). 1-Nitropyrene (1-NP), a representative example, is a bacterial mutagen and an animal tumorigen and h...

    Karam El-Bayoumy, Ajit K. Roy, Stephen S. Hecht in Nitroarenes (1990)

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    Chapter

    The Possible Role of Nitroarenes in Human Cancer

    In this paper, we consider the possible role of nitroarenes as causative compounds for human cancer. At the outset, it is important to recognize that adequate data to answer this question are not available. Ho...

    Stephen S. Hecht, Karam El-Bayoumy in Nitroarenes (1990)