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  1. No Access

    Article

    DNA-driven condensation assembles the meiotic DNA break machinery

    The accurate segregation of chromosomes during meiosis—which is critical for genome stability across sexual cycles—relies on homologous recombination initiated by DNA double-strand breaks (DSBs) made by the Sp...

    Corentin Claeys Bouuaert, Stephen Pu, Juncheng Wang, Cédric Oger, Dima Daccache… in Nature (2021)

  2. No Access

    Article

    Structural and functional characterization of the Spo11 core complex

    Spo11, which makes DNA double-strand breaks (DSBs) that are essential for meiotic recombination, has long been recalcitrant to biochemical study. We provide molecular analysis of Saccharomyces cerevisiae Spo11 pu...

    Corentin Claeys Bouuaert, Sam E. Tischfield… in Nature Structural & Molecular Biology (2021)