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Open AccessReanalysis of cluster randomised trial data to account for exposure misclassification using a per-protocol and complier-restricted approach
The intention-to-treat (ITT) analysis of the Applying Wolbachia to Eliminate Dengue (AWED) trial estimated a protective efficacy of 77.1% for participants resident in areas randomised to receive releases of wMel-...
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Article
Open AccessDisruption of spatiotemporal clustering in dengue cases by wMel Wolbachia in Yogyakarta, Indonesia
Dengue exhibits focal clustering in households and neighborhoods, driven by local mosquito population dynamics, human population immunity, and fine scale human and mosquito movement. We tested the hypothesis t...
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Open AccessAssociation between increased signal intensity at the proximal patellar tendon and patellofemoral geometry in community-based asymptomatic middle-aged adults: a cross-sectional study
Histological and epidemiological data suggest that increased signal intensity at the proximal patellar tendon on magnetic resonance imaging is a response to tendon loading. As patellofemoral geometry is a medi...
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Article
Open AccessUpdate to the AWED (Applying Wolbachia to Eliminate Dengue) trial study protocol: a cluster randomised controlled trial in Yogyakarta, Indonesia
The AWED (Applying Wolbachia to Eliminate Dengue) trial is a parallel, two-arm, non-blinded cluster randomised controlled trial that is under way in Yogyakarta, Indonesia, with the aim of measuring the efficacy o...
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Article
Diabetes management and treatment approaches outside of North America and West Europe in 2006 and 2015
The impact of introducing new classes of glucose-lowering medication (GLM) on diabetes management remains unclear, especially outside North America and Western Europe. Therefore, we aimed to analyse trends in ...
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Article
Urine metabolites are associated with glomerular lesions in type 2 diabetes
Little is known about the association of urine metabolites with structural lesions in persons with diabetes.
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Open AccessEstimating the proportion of metabolic health outcomes attributable to obesity: a cross-sectional exploration of body mass index and waist circumference combinations
Recent evidence suggests that a substantial subgroup of the population who have a high-risk waist circumference (WC) do not have an obese body mass index (BMI). This study aimed to explore whether including th...
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The performance of diabetes risk prediction models in new populations: the role of ethnicity of the development cohort
It is believed that diabetes risk scores need to be ethnic specific. However, this prerequisite has not been tested. We examined the performance of several risk models, developed in various populations, in a E...
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Open AccessFat mass is associated with disabling foot pain
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Open AccessThe associations between indices of patellofemoral geometry and knee pain and patella cartilage volume: a cross-sectional study
Whilst patellofemoral pain is one of the most common musculoskeletal disorders presenting to orthopaedic clinics, sports clinics, and general practices, factors contributing to its development in the absence o...
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Open AccessThe association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study
To examine the natural history of subchondral bone cysts and to determine whether knee cartilage loss and risk of joint replacement is higher in knees with cysts, compared with those with bone marrow lesions (...