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Open AccessAssessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates
Therapeutic approaches targeting proteins on the surface of cancer cells have emerged as an important strategy for precision oncology. To capitalize on the potential impact of drugs targeting surface proteins,...
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Article
Automated prostate gland segmentation in challenging clinical cases: comparison of three artificial intelligence methods
Automated methods for prostate segmentation on MRI are typically developed under ideal scanning and anatomical conditions. This study evaluates three different prostate segmentation AI algorithms in a challeng...
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Article
Ipsilateral hemigland prostate biopsy may underestimate cancer burden in patients with unilateral mpMRI-visible lesions
To evaluate the cancer detection rates of reduced-core biopsy schemes in patients with unilateral mpMRI-visible intraprostatic lesions and to analyze the contribution of systematic biopsy cores in clinically s...
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Article
Deep learning-based artificial intelligence for prostate cancer detection at biparametric MRI
To present fully automated DL-based prostate cancer detection system for prostate MRI.
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Article
Apical periurethral transition zone lesions: MRI and histology findings
Apical periurethral transition zone (TZ) cancers can pose unique problems for surgery and radiation therapy. Here, we describe the appearance of such cancers on multiparametric MRI (mpMRI) and correlate this w...
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Article
Open AccessArtificial intelligence for the detection of COVID-19 pneumonia on chest CT using multinational datasets
Chest CT is emerging as a valuable diagnostic tool for clinical management of COVID-19 associated lung disease. Artificial intelligence (AI) has the potential to aid in rapid evaluation of CT scans for differe...
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Open AccessA case report of multiple primary prostate tumors with differential drug sensitivity
Localized prostate cancers are genetically variable and frequently multifocal, comprising spatially distinct regions with multiple independently-evolving clones. To date there is no understanding of whether th...
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Article
Quantification of bone flare on 18F-NaF PET/CT in metastatic castration-resistant prostate cancer
Bone flare has been observed on 99mTc-MDP bone scans of patients with metastatic castration-resistant prostate cancer (mCRPC). This exploratory study investigates bone flare in mCRPC patients receiving androgen r...
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Evaluating the size criterion for PI-RADSv2 category 5 upgrade: is 15 mm the best threshold?
The purpose of the study was to determine if the ≥ 15 mm threshold currently used to define PIRADS 5 lesions is the optimal size threshold for predicting high likelihood of clinically significant (CS) cancers.