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  1. No Access

    Article

    Induction of GM1a/GD1b synthase triggers complex ganglioside expression and alters neuroblastoma cell behavior; a new tumor cell model of ganglioside function

    Neuroblastoma is the most common extracranial solid tumor in children and tumor ganglioside composition has been linked to its biological and clinical behavior. We recently found that high expression of comple...

    Lixian Dong, Yihui Liu, Anamaris M. Colberg-Poley, Karen Kaucic… in Glycoconjugate Journal (2011)

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    Article

    Structural characterization andin vivo immunosuppressive activity of neuroblastoma GD2

    Shedding of neuroblastoma gangliosides is positively correlated with tumour progression in patients with neuroblastoma. In assessing the biological activity of these ganglioside molecules, we recently found th...

    Ruixiang Li, Douglas Gage, Robert Mckallip, Stephan Ladisch in Glycoconjugate Journal (1996)

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    Chapter

    Biological Significance of Tumor Gangliosides: Shedding, Transfer, and Immunosuppression

    Tumor formation is a complex, multiple-step process influenced by many factors. Local interactions between the tumor cell and the host are critical to tumor formation, and it is becoming recognized that the re...

    Stephan Ladisch in Frontiers in Bioactive Lipids (1996)