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    Article

    Multiplexed proteome analysis with neutron-encoded stable isotope labeling in cells and mice

    This NeuCode SILAC/SILAM protocol uses neutron-coded lysine derivatives to improve stable isotope labeling of amino acids in cells or mice, enabling multiplexed comparison of proteomes from different samples b...

    Katherine A Overmyer, Stefka Tyanova, Alex S Hebert in Nature Protocols (2018)

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    Article

    The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

    MaxQuant is a platform for mass spectrometry-based proteomics data analysis. It includes a peptide database search engine, called Andromeda, and expanding capability to handle data from most quantitative prote...

    Stefka Tyanova, Tikira Temu, Juergen Cox in Nature Protocols (2016)

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    Article

    The Perseus computational platform for comprehensive analysis of (prote)omics data

    Perseus is a comprehensive, user-friendly software platform for the biological analysis of quantitative proteomics data. It is intended to help biologists with little bioinformatics training to interpret prote...

    Stefka Tyanova, Tikira Temu, Pavel Sinitcyn, Arthur Carlson, Marco Y Hein in Nature Methods (2016)

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    Article

    Cell type– and brain region–resolved mouse brain proteome

    The authors performed a comprehensive proteome analysis of the adult mouse brain, its major regions and CNS cell types at a depth of >13,000 proteins. This new resource represents the largest collection of cel...

    Kirti Sharma, Sebastian Schmitt, Caroline G Bergner, Stefka Tyanova in Nature Neuroscience (2015)